Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2B | Q02880 | 1/20 | 0.68 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.58 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.58 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.58 |
| ▸ | PIM1 | P11309 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | FGR | P09769 | 1/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 8/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | POLB | P06746 | 6/20 | 0.57 |
| ▸ | BLM | P54132 | 5/20 | 0.57 |
| ▸ | NSD2 | O96028 | 3/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | MMP14 | P50281 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MTOR | P42345 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357976 | 0.91 | TOP2B (0.81) | TOP2BPIM1MEN1KMT2APOLB | |
| SCHEMBL1426702 | 0.91 | TOP2B (0.81) | TOP2BPIM1MEN1KMT2APOLB | |
| SCHEMBL10581062 | 0.87 | NSD2 (0.63) | TOP2BADORA2ACSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL8947726 | 0.86 | TOP2B (0.74) | TOP2BPIM1MEN1KMT2APOLB | |
| SCHEMBL455300 | 0.84 | TOP2B (0.72) | TOP2BPIM1MEN1KMT2APOLB | |
| Methylamine SCHEMBL10780560 | 0.84 | ADORA2A (0.56) | TOP2BADORA2ACSNK1A1CSNK1DCSNK1G1 | |
| SCHEMBL11576965 | 0.83 | TOP2B (0.70) | TOP2BPIM1MEN1KMT2APOLB | |
| SCHEMBL23404 | 0.83 | TOP2B (0.70) | TOP2BPIM1MEN1KMT2APOLB | |
| SCHEMBL8428873 | 0.83 | TOP2B (0.70) | TOP2BCSNK1A1CSNK1DCSNK1G1PIM1 | |
| SCHEMBL29670831 | 0.83 | TOP2B (0.70) | TOP2BPIM1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114979-B2 | Di-alpha amino anthraquinone compositions | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2012-02-14 | — | — | US | disclosed |
| US-20110060150-A1 | METHOD OF DETECTING FLUORESCENCE | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2011-03-10 | — | — | US | disclosed |
| EP-2281798-A1 | Anthraquinone quencher dyes, their methods of preparation and use | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2011-02-09 | — | — | EP | disclosed |
| US-7803536-B2 | Methods of detecting fluorescence with anthraquinone quencher dyes | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2010-09-28 | — | — | US | disclosed |
| US-20040110308-A1 | Anthraquinone quencher dyes, their methods of preparation and use | INTEGRATED DNA TECHNOLOGIES, INC. (US) | 2004-06-10 | — | — | US | disclosed |
| US-3971740-A | DYES FOR POLYESTER FIBERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110060150-A1 | METHOD OF DETECTING FLUORESCENCE | ANXA5, ANTXR2, ANXA4 | TOP2B 1371/4885ADORA2A 258/4885CSNK1A1 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.