Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10354233 | 0.74 | HTR6 (0.62) | HTR6AKR1B1TSHRALDH1A1HSD17B10 | |
| SCHEMBL6403890 | 0.71 | HTR6 (0.50) | HTR6AKR1B1TSHRALDH1A1HSD17B10 | |
| SCHEMBL31345714 | 0.69 | HTR6 (0.54) | HTR6AKR1B1TSHRALDH1A1HSD17B10 | |
| SCHEMBL28965981 | 0.69 | HTR6 (0.48) | HTR6AKR1B1TSHRALDH1A1HSD17B10 | |
| SCHEMBL16369913 | 0.69 | HTR6 (0.59) | HTR6AKR1B1TSHRALDH1A1HSD17B10 | |
| SCHEMBL27469595 | 0.69 | — | — | |
| (Phenylsulfonyl)Benzene SCHEMBL29473549 | 0.68 | HTR6 (1.00) | HTR6TSHRALDH1A1HSD17B10TDP1 | |
| (Phenylsulfonyl)Benzene SCHEMBL29775288 | 0.68 | HTR6 (1.00) | HTR6TSHRALDH1A1HSD17B10TDP1 | |
| (Phenylsulfonyl)Benzene SCHEMBL13735236 | 0.68 | HTR6 (1.00) | HTR6TSHRALDH1A1HSD17B10TDP1 | |
| (Phenylsulfonyl)Benzene SCHEMBL29450723 | 0.68 | HTR6 (1.00) | HTR6TSHRALDH1A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874081-A | High-affinity anti-MERKT antibodies and uses thereof | 茵思博纳公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-113795263-A | Engineered erythroid cells comprising loadable antigen-presenting polypeptides and methods of use | 鲁比厄斯治疗法股份有限公司 | 2021-12-14 | — | — | CN | disclosed |
| CN-111491670-A | Radiolabelling of polypeptides | 詹森生物科技公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-109641038-A | The conjugate of target cell surface editor | 小利兰·斯坦福大学理事会 | 2019-04-16 | — | — | CN | disclosed |