SCHEMBL6403890

SCHEMBL6403890

O=S(=O)(c1ccccc1)c1ccon1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.50
AKR1B1 P15121 1/20 0.44
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ABCB1 P08183 7/20 0.41
ABCC1 P33527 7/20 0.41
NLRP3 Q96P20 1/20 0.41
AGTR1 P30556 1/20 0.40
PKM P14618 2/20 0.40
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL5706278 0.73 CA2 (0.47) CA12CA1CA2CA9
SCHEMBL7416555 0.72 PKM (0.46) ALDH1A1PKMCA12CA9
SCHEMBL10354233 0.72 HTR6 (0.62) HTR6AKR1B1TSHRALDH1A1HSD17B10
SCHEMBL28287666 0.71 HTR6 (0.48) HTR6AKR1B1TSHRALDH1A1HSD17B10
SCHEMBL25380537 0.71 HTR6 (0.48) HTR6AKR1B1TSHRALDH1A1HSD17B10
Naphthalene SCHEMBL7850037 0.71 LMNA (0.41) CA12CA1CA2CA9
SCHEMBL4804428 0.70
SCHEMBL16369913 0.70 HTR6 (0.59) HTR6AKR1B1TSHRALDH1A1HSD17B10
(Phenylsulfonyl)Benzene SCHEMBL29473549 0.69 HTR6 (1.00) HTR6TSHRALDH1A1HSD17B10TDP1
(Phenylsulfonyl)Benzene SCHEMBL13735236 0.69 HTR6 (1.00) HTR6TSHRALDH1A1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116600643-A Herbicide mixture, herbicide composition, method for controlling undesired vegetation and kit 安道麦阿甘有限公司 2023-08-15 CN disclosed
CN-108366563-A Herbicide mixture and preparation for potatoes 阿达玛阿甘有限公司 2018-08-03 CN disclosed
CN-102791128-A Noxious organism control agent composition for agricultural and horticultural applications, and use thereof NIHON NOHYAKU CO LTD 2012-11-21 CN disclosed
US-20050171358-A1 Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide SDS BIOTECH K.K. (JP) 2005-08-04 US disclosed
US-5739396-A CHIRAL COMPOUND COMPRISING CHIRAL BACKBONE TO WHICH IS BOUND TWO OR THREE METAL BINDING MOIETIES STANFORD UNIVERSITY (US) 1998-04-14 US disclosed
EP-0382628-B1 Aminoalkoxylphenyl derivatives, process for their preparation and compositions containing them SANOFI ELF (FR) 1994-05-04 EP disclosed
EP-0382618-A2 Aminoalkoxyphenyl derivatives, process for their preparation and compositions containing them SANOFI (FR) 1990-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050171358-A1 Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide AHR, ERG28, CYP1A2 HTR6 1596/4885AKR1B1 100/4885TSHR 705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.