Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.66 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.66 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.64 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30417619 | 0.89 | GABRA1 (0.78) | GABRA1GABRB2GABRB1GABRA3L3MBTL1 | |
| SCHEMBL7284420 | 0.89 | GABRA1 (0.78) | GABRA1GABRB2GABRB1GABRA3L3MBTL1 | |
| SCHEMBL4742551 | 0.86 | GABRA1 (0.63) | GABRA1GABRB2GABRB1GABRA3L3MBTL1 | |
| SCHEMBL30906938 | 0.86 | GABRA1 (0.63) | GABRA1GABRB2GABRB1GABRA3L3MBTL1 | |
| SCHEMBL1430217 | 0.86 | GABRA1 (0.81) | GABRA1GABRB2GABRB1GABRA3L3MBTL1 | |
| SCHEMBL1430520 | 0.86 | GABRA1 (0.63) | GABRA1GABRB2GABRB1GABRA3L3MBTL1 | |
| SCHEMBL30906939 | 0.86 | GABRA1 (0.63) | GABRA1GABRB2GABRB1GABRA3L3MBTL1 | |
| SCHEMBL7294152 | 0.86 | GABRA1 (0.63) | GABRA1GABRB2GABRB1GABRA3L3MBTL1 | |
| SCHEMBL10474074 | 0.85 | MEN1 (0.66) | GABRA1GABRB2GABRB1GABRA3L3MBTL1 | |
| SCHEMBL2977304 | 0.85 | GABRA1 (0.62) | GABRA1GABRB2GABRB1GABRA3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651247-A | A kind of green high-efficient synthetic method of carbostyril compound | 云南民族大学 | 2019-04-19 | — | — | CN | disclosed |