Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.63 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.63 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.62 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30906938 | 1.00 | GABRA1 (0.63) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL30906939 | 1.00 | GABRA1 (0.63) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL1366633 | 0.90 | GABRA1 (0.74) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL30418194 | 0.90 | GABRA1 (0.74) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL28287752 | 0.86 | GABRA1 (0.66) | GABRA1GABRB2GABRB1GABRA3NR4A2 | |
| SCHEMBL1430520 | 0.84 | GABRA1 (0.63) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL4742551 | 0.84 | GABRA1 (0.63) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL1430217 | 0.84 | GABRA1 (0.81) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL28289180 | 0.84 | GABRA1 (0.66) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL10474074 | 0.83 | MEN1 (0.66) | GABRA1GABRB2GABRB1GABRA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024104344-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE AND USE THEREOF | 沈阳中化农药化工研发有限公司 | 2024-05-23 | — | — | WO | disclosed |
| CN-118047721-A | Quinoline carboxylic acid derivative and application thereof | 沈阳中化农药化工研发有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-114456110-A | Synthesis method of 7-chloro-4-hydroxyquinoline-3-carboxylic acid | 重庆南松凯博生物制药有限公司 | 2022-05-10 | — | — | CN | disclosed |
| WO-2017198196-A1 | QUINOLINE DERIVATIVE HAVING ANTI-TUMOR ACTIVITY | 王子厚 | 2017-11-23 | — | — | WO | disclosed |
| US-5438064-A | For suppressing the binding of bradykinins to pain receptors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-08-01 | — | — | US | disclosed |
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5081121-A | Cardiotonic agents | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0376870-A1 | A new organosilylpolyphosphoric reagent, its preparation and application to the process of synthesis of 3-carboxyquinolones or azaquinolones and their salts | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1990-07-04 | — | — | EP | disclosed |
| US-4017622-A | BACTERICIDES | DAINIPPON PHARMACEUTICAL CO., LTD. (JA) | 1977-04-12 | — | — | US | disclosed |