Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MDH2 | P40926 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28289122 | 0.89 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2LMNATP53RAB9A | |
| SCHEMBL4342972 | 0.84 | CYP1A2 (0.62) | ALDH1A1SMN1; SMN2HPGDMDH2MEN1 | |
| SCHEMBL28287762 | 0.83 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2LMNATP53RAB9A | |
| SCHEMBL29254481 | 0.83 | TP53 (0.55) | ALDH1A1SMN1; SMN2LMNATP53RAB9A | |
| SCHEMBL30951610 | 0.83 | TP53 (0.55) | ALDH1A1SMN1; SMN2LMNATP53RAB9A | |
| SCHEMBL12707173 | 0.82 | CFTR (0.61) | ALDH1A1SMN1; SMN2LMNATP53RAB9A | |
| SCHEMBL6285541 | 0.81 | NR4A2 (0.58) | ALDH1A1SMN1; SMN2LMNATP53RAB9A | |
| SCHEMBL28287759 | 0.80 | TUBB1 (0.64) | ALDH1A1SMN1; SMN2LMNATP53RAB9A | |
| SCHEMBL28289127 | 0.79 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2LMNATP53RAB9A | |
| SCHEMBL28287771 | 0.79 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2LMNATP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651247-A | A kind of green high-efficient synthetic method of carbostyril compound | 云南民族大学 | 2019-04-19 | — | — | CN | disclosed |