SCHEMBL3519320

SCHEMBL3519320

CC(=O)CC(=O)CC(C)=O.[Co]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.55
KDM6B O15054 1/20 0.55
KDM5C P41229 1/20 0.55
EGLN1 Q9GZT9 1/20 0.55
PHF8 Q9UPP1 1/20 0.55
KDM2A Q9Y2K7 1/20 0.55
MGAM O43451 1/20 0.47
GAA P10253 1/20 0.47
SI P14410 1/20 0.47
MGAM2 Q2M2H8 1/20 0.47
ALDH1A1 P00352 4/20 0.44
TDP1 Q9NUW8 3/20 0.44
HTT P42858 2/20 0.43
TRPA1 O75762 1/20 0.41
LMNA P02545 4/20 0.36
CA2 P00918 1/20 0.35
PTGS1 P23219 1/20 0.35
MMP12 P39900 1/20 0.35
SLC15A2 Q16348 1/20 0.35
NFKB1 P19838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235434 0.96 KDM4E (0.58) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL10936077 0.92 KDM4E (0.55) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL26967576 0.92 KDM4E (0.55) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28338656 0.92 KDM4E (0.55) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28123714 0.92 KDM4E (0.55) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28706026 0.92 KDM4E (0.55) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28634328 0.89 KDM4E (0.52) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL11219945 0.84 MGAM (0.53) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL1686202 0.84 MGAM (0.53) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL588255 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8852555-B2 Process for production of surface-coated inorganic particles TOKYO INSTITUTE OF TECHNOLOGY (JP) 2014-10-07 US disclosed
EP-2184262-B1 PROCESS FOR PRODUCTION OF SURFACE-COATED INORGANIC PARTICLES TOKYO INST TECH (JP) 2012-12-26 EP disclosed
US-20100254908-A1 PROCESS FOR PRODUCTION OF SURFACE-COATED INORGANIC PARTICLES TOKYO INSTITUTE OF TECHNOLOGY (JP) 2010-10-07 US disclosed
EP-2184262-A1 PROCESS FOR PRODUCTION OF SURFACE-COATED INORGANIC PARTICLES Tokyo Institute of Technology (JP) 2010-05-12 EP disclosed
CN-1281470-A Cycloolefin polymer reduced in catalyst residue content, use thereof, and process for producing same TEIJIN LTD (JP) 2001-01-24 CN disclosed
US-4641059-A CHELATION OF ORGANOMETAL ACCELERATOR IN ADHESIVE RESINS; HIGH RESOLUTION SONY CORPORATION (JP) 1987-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100254908-A1 PROCESS FOR PRODUCTION OF SURFACE-COATED INORGANIC PARTICLES SLC27A1, SLC27A2, CS KDM4E 3850/4885KDM6B 3492/4885KDM5C 3472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.