SCHEMBL235434

SCHEMBL235434

CC(=O)CC(=O)CC(C)=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.58
KDM6B O15054 1/20 0.58
KDM5C P41229 1/20 0.58
EGLN1 Q9GZT9 1/20 0.58
PHF8 Q9UPP1 1/20 0.58
KDM2A Q9Y2K7 1/20 0.58
MGAM O43451 1/20 0.50
GAA P10253 1/20 0.50
SI P14410 1/20 0.50
MGAM2 Q2M2H8 1/20 0.50
ALDH1A1 P00352 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
HTT P42858 2/20 0.45
TRPA1 O75762 1/20 0.44
LMNA P02545 4/20 0.39
CA2 P00918 1/20 0.38
PTGS1 P23219 1/20 0.38
MMP12 P39900 1/20 0.38
SLC15A2 Q16348 1/20 0.37
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3519320 0.96 KDM4E (0.55) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28706026 0.96 KDM4E (0.55) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL10936077 0.96 KDM4E (0.55) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28634328 0.93 KDM4E (0.52) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28887 0.87 EGLN1 (0.62) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL321597 0.87 EGLN1 (0.62) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL61062 0.85 KDM4E (0.78) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL23777918 0.84 KDM4E (0.46) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL10564199 0.84 KDM4E (0.46) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL16518799 0.84 KDM4E (0.46) KDM4EKDM6BKDM5CEGLN1PHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 682 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118496812-A Preparation method of low-compression set single-component addition type liquid silicone rubber for CIPG (copper-in-place) process 广州天宸高新材料有限公司 2024-08-16 CN claimed
CN-118307001-A Method for preparing high-magnification silicon-based composite anode material by utilizing photovoltaic silicon cutting waste 昆明理工大学 2024-07-09 CN claimed
CN-113710718-B Stabilized silane-modified polymer compositions and methods 迈图高新材料公司 2024-06-25 CN claimed
EP-4043610-B1 METAL SURFACE-TREATING AGENT, AND METAL MATERIAL WITH COATING FILM AND METHOD FOR MANUFACTURING SAME NIHON PARKERIZING (JP) 2024-05-29 EP claimed
CN-113908833-B Reverse water gas shift catalyst and preparation method and application thereof 源创核新(北京)新材料科技有限公司 2024-04-02 CN claimed
CN-116554372-A Preparation method of low-entanglement ultra-high molecular weight polyethylene 中国科学院长春应用化学研究所 2023-08-08 CN claimed
US-11424006-B2 Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide PSOMAGEN, INC. (US) 2022-08-23 US claimed
EP-4012395-A1 FREE-FLOW ELECTROPHORESIS METHOD FOR SEPARATING ANALYTES Weber, Gerhard (DE) 2022-06-15 EP claimed
CN-113908833-A Reverse water gas shift catalyst and preparation method and application thereof 源创核新(北京)新材料科技有限公司 2022-01-11 CN claimed
CN-113278004-A Preparation method of aliphatic cyclic polycarbonate 源创核新(北京)新材料科技有限公司 2021-08-20 CN claimed
EP-1164633-A2 Method for etching an electrode in a semiconductor device NEC CORPORATION (JP) 2001-12-19 EP claimed
EP-0907762-B1 CHROMATE-FREE CONVERSION LAYER AND PROCESS FOR PRODUCING THE SAME SURTEC PRODUKTE UND SYSTEME FU (DE) 2001-10-17 EP claimed
US-5877210-A CONTROLLING IMMUNE RESPONSE BRISTOL-MYERS SQUIBB COMPANY (US) 1999-03-02 US claimed
US-5858386-A CONTROLLED RELEASE OF BIOACTIVE AGENTS ON DRY PRE-FLOODED LAND; WATER SOLUBLE, BIODEGRADABLE COATING OF FATTY ALCOHOLS, FATTY ACIDS, FATTY ESTERS OR PHTHALYL ESTERS; MOSQUITO, WEED CONTROL; NO SUPERABSORBENT POLYMERS LEE COUNTY MOSQUITO CONTROL DISTRICT (US) 1999-01-12 US claimed
US-5858384-A Controlled delivery compositions and processes for treating organisms in a column of water or on land LEE COUNTY MOSQUITO CONTROL DISTRICT (US) 1999-01-12 US claimed
US-5846553-A Controlled delivery compositions and processes for treating organisms in a column of water or on land LEE COUNTY MOSQUITO CONTROL DISTRICT (US) 1998-12-08 US claimed
US-5583242-A VANADYL COMPLEXES BRISTOL-MYERS SQUIBB COMPANY (US) 1996-12-10 US claimed
US-5565491-A FOR TREATMENT OF DISEASES MARKED BY MALIGNANT PROLIFERATION OF B CELLS, SUCH AS LEUKEMIA AND LYMPHOMAS; ANTICARCINOGENIC AGENTS BRISTOL-MYERS SQUIBB COMPANY (US) 1996-10-15 US claimed
US-5091591-A Ammonium, alkali, alkaline earth metal or zinc salt of aliphatic mono ro dicarboxalic acid as stabilizers GENERAL ELECTRIC COMPANY (US) 1992-02-25 US claimed
EP-0470898-A1 Piezoelectric ceramic with controlled porosity THOMSON-CSF (FR) 1992-02-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11424006-B2 Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide PNMT, MAOA, HNMT KDM4E 733/4885KDM6B 565/4885KDM5C 280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.