⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000974 | 1.00 | — | — | |
| SCHEMBL57967 | 0.96 | — | — | |
| SCHEMBL290664 | 0.83 | — | — | |
| SCHEMBL3857734 | 0.81 | CES1 (0.32) | — | |
| SCHEMBL514303 | 0.79 | CES1 (0.35) | — | |
| SCHEMBL581064 | 0.79 | CES1 (0.35) | — | |
| SCHEMBL5356778 | 0.79 | CES1 (0.35) | — | |
| SCHEMBL2305639 | 0.79 | CES1 (0.35) | — | |
| SCHEMBL2285351 | 0.79 | CES1 (0.35) | — | |
| SCHEMBL5651324 | 0.79 | CES1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213652-B1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | UNIV PENNSYLVANIA (US) | 2014-10-22 | — | — | EP | disclosed |
| US-8465726-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-06-18 | — | — | US | disclosed |
| US-7858072-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-12-28 | — | — | US | disclosed |
| US-20100266500-A1 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-10-21 | — | — | US | disclosed |
| US-7807135-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-10-05 | — | — | US | disclosed |
| EP-2213652-A1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | The Trustees of The University of Pennsylvania (US) | 2010-08-04 | — | — | EP | disclosed |
| EP-1841465-A4 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | UNIV PENNSYLVANIA (US) | 2009-04-01 | — | — | EP | disclosed |
| EP-1838298-A4 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | UNIV PENNSYLVANIA (US) | 2009-03-04 | — | — | EP | disclosed |
| EP-1841465-A2 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | The Trustees of The University of Pennsylvania (US) | 2007-10-10 | — | — | EP | disclosed |
| EP-1838298-A2 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | The Trustees of The University of Pennsylvania (US) | 2007-10-03 | — | — | EP | disclosed |
| US-20060269474-A1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-11-30 | — | — | US | disclosed |
| US-20060269473-A1 | Stilbene derivatives and their use for binding and imaging amyoid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-11-30 | — | — | US | disclosed |
| WO-2006078384-A2 | STILBENE DERIVATIVES AND THEIR USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-07-27 | — | — | WO | disclosed |
| WO-2006066104-A2 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-06-22 | — | — | WO | disclosed |