SCHEMBL514303

SCHEMBL514303

C[SiH](C)C(C)(C)COCCCCCCBr

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5356778 1.00 CES1 (0.35) CES1
SCHEMBL581064 1.00 CES1 (0.35) CES1
SCHEMBL5651324 1.00 CES1 (0.35) CES1
SCHEMBL2285351 1.00 CES1 (0.35) CES1
SCHEMBL2805477 1.00 CES1 (0.35) CES1
SCHEMBL2305639 1.00 CES1 (0.35) CES1
SCHEMBL3857734 0.98 CES1 (0.32) CES1
SCHEMBL290664 0.92
SCHEMBL15792000 0.80 CES1 (0.35) CES1
SCHEMBL8000974 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120028191-A1 Azide Functionalized Poly(3-Hexylthiophene) and Method of Forming Same BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) 2012-02-02 US claimed
EP-4737504-A2 CATIONIC LIPID, LIPOSOME CONTAINING CATIONIC LIPID, AND NUCLEIC-ACID PHARMACEUTICAL COMPOSITION CONTAINING LIPOSOME AND FORMULATION AND APPLICATION THEREOF Xiamen Sinopeg Biotech Co., Ltd. (CN) 2026-05-06 EP disclosed
EP-4276090-B1 CATIONIC LIPID, LIPOSOME CONTAINING CATIONIC LIPID, AND NUCLEIC-ACID PHARMACEUTICAL COMPOSITION CONTAINING LIPOSOME AND PREPARATION AND APPLICATION THEREOF XIAMEN SINOPEG BIOTECH CO LTD (CN) 2026-04-29 EP disclosed
US-12492202-B2 Macrocyclic PAD4 inhibitors useful as immunosuppressant BRISTOL-MYERS SQUIBB COMPANY (US) 2025-12-09 US disclosed
US-20250346554-A1 METHOD FOR PURIFYING COMPOSITION JSR CORPORATION (JP) 2025-11-13 US disclosed
EP-4450485-A1 METHOD FOR PURIFYING COMPOSITION JSR Corporation (JP) 2024-10-23 EP disclosed
US-20240342088-A1 CATIONIC LIPID, LIPOSOME CONTAINING CATIONIC LIPID, AND NUCLEIC-ACID PHARMACEUTICAL COMPOSITION CONTAINING LIPOSOME AND FORMULATION AND APPLICATION THEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2024-10-17 US disclosed
EP-4276090-A1 CATIONIC LIPID, LIPOSOME CONTAINING CATIONIC LIPID, AND NUCLEIC-ACID PHARMACEUTICAL COMPOSITION CONTAINING LIPOSOME AND PREPARATION AND APPLICATION THEREOF Xiamen Sinopeg Biotech Co., Ltd. (CN) 2023-11-15 EP disclosed
US-20230203039-A1 MACROCYCLIC PAD4 INHIBITORS USEFUL AS IMMUNOSUPPRESSANT BRISTOL MYERS SQUIBB CO (US) 2023-06-29 US disclosed
WO-2023112939-A1 METHOD FOR PURIFYING COMPOSITION JSR株式会社 2023-06-22 WO disclosed
US-20050288344-A1 Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases MICRODOSE THERAPEUTX, INC. 2005-12-29 US disclosed
WO-2005121150-A1 POLYMERISABLE THIENO[3,2-b]THIOPHENES MERCK PATENT GMBH (DE) 2005-12-22 WO disclosed
WO-2005086974-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-09-22 WO disclosed
WO-2005080369-A2 REACTIVE MESOGENIC CHARGE TRANSPORT COMPOUNDS CONTAINING AT LEAST TWO THIOPHENE GROUPS MERCK PATENT GMBH (DE) 2005-09-01 WO disclosed
US-20050184274-A1 Reactive mesogenic charge transport compounds MERCK PATENT GMBH (DE) 2005-08-25 US disclosed
EP-1545513-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PNEUMOVIRUS INFECTION AND ASSOCIATED DISEASES Viropharma Incorporated (US) 2005-06-29 EP disclosed
US-20050090640-A1 Mono-, oligo-and polythieno[2,3-b]thiophenes FLEXENABLE TECHNOLOGY LIMITED (GB) 2005-04-28 US disclosed
WO-2005019184-A1 COMPOUNDS, METHODS AND FORMULATIONS FOR THE ORAL DELIVERY OF A GLUCAGON LIKE PEPTIDE (GLP)-1 COMPOUND OR AN MELANOCORTIN 4 RECEPTOR (MC4) AGONIST PEPTIDE ELI LILLY AND COMPANY (US) 2005-03-03 WO disclosed
EP-1510535-A1 Mono-, Oligo- and Polythieno(2,3-b)thiophenes MERCK PATENT GmbH (DE) 2005-03-02 EP disclosed
WO-2004014316-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING PNEUMOVIRUS INFECTION AND ASSOCIATED DISEASES VIROPHARMA INCORPORATED (US) 2004-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346554-A1 METHOD FOR PURIFYING COMPOSITION HSD17B7, AKR1C3, DEGS1 CES1 79/4885
US-20120028191-A1 Azide Functionalized Poly(3-Hexylthiophene) and Method of Forming Same NUDT1, NMT1, MPST CES1 4849/4885
US-20050288344-A1 Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases TTPA, HAVCR2, ZC3HAV1 CES1 827/4885
US-12492202-B2 Macrocyclic PAD4 inhibitors useful as immunosuppressant PADI4, PADI1, PADI2 CES1 26/4885
US-20240342088-A1 CATIONIC LIPID, LIPOSOME CONTAINING CATIONIC LIPID, AND NUCLEIC-ACID PHARMACEUTICAL COMPOSITION CONTAINING LIPOSOME AND FORMULATION AND APPLICATION THEREOF NPC1, SLC27A1, SLC7A1 CES1 274/4885
US-20230203039-A1 MACROCYCLIC PAD4 INHIBITORS USEFUL AS IMMUNOSUPPRESSANT PADI4, PADI1, PADI2 CES1 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.