SCHEMBL57967

SCHEMBL57967

C[SiH](C)C(C)(C)COCCBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2828995 0.96
SCHEMBL8000974 0.96
SCHEMBL290664 0.86
SCHEMBL3857734 0.85 CES1 (0.32)
SCHEMBL5356778 0.83 CES1 (0.35)
SCHEMBL581064 0.83 CES1 (0.35)
SCHEMBL5651324 0.83 CES1 (0.35)
SCHEMBL2305639 0.83 CES1 (0.35)
SCHEMBL2285351 0.83 CES1 (0.35)
SCHEMBL514303 0.83 CES1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2013 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12459907-B2 Process for the production of ozanimod EGIS GYOGYSZERGYAR ZRT. (HU) 2025-11-04 US claimed
CN-117949549-A Method for measuring sorbitol nucleating agent content in polypropylene 中国石油化工股份有限公司 2024-04-30 CN claimed
EP-3630738-B1 PROCESS FOR THE PRODUCTION OF OZANIMOD EGYT GYOGYSZERVEGYESZETI GYAR (HU) 2023-07-19 EP claimed
CN-115746228-B AB prepared by using polyfluorene as initiator 2 Method for synthesizing block copolymer 常州工程职业技术学院 2023-05-09 CN claimed
CN-115746228-A Preparation of AB by using polyfluorene as initiator 2 Method for synthesizing block copolymer 常州工程职业技术学院 2023-03-07 CN claimed
CN-115286616-A Tetrahydroisoquinoline and isoindoline compound capable of binding sigma-2 receptor, preparation method and application thereof 北京师范大学 2022-11-04 CN claimed
WO-2022037365-A1 DOUBLE-TARGET INHIBITOR TARGETING FGFR AND HDAC, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF, PHARMACEUTICAL COMPOSITION AND MEDICAMENT 四川大学华西医院 2022-02-24 WO claimed
CN-112920167-A Double-target inhibitor targeting FGFR and HDAC, preparation method and application thereof, pharmaceutical composition and medicament 四川大学华西医院 2021-06-08 CN claimed
EP-3406142-B1 SELECTIVE SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS CELGENE INT II SARL (CH) 2020-12-23 EP claimed
CN-112062785-A Preparation method of ozapimod and intermediate thereof 广东东阳光药业有限公司 2020-12-11 CN claimed
CN-110997645-A Preparation method of ozanimod 埃吉斯制药公司 2020-04-10 CN claimed
US-20200087269-A1 PROCESS FOR THE PRODUCTION OF OZANIMOD EGIS GYOGYSZERGYAR ZRT. (HU) 2020-03-19 US claimed
WO-2026106389-A1 NMT INHIBITOR AND USE THEREOF 주식회사 이노보테라퓨틱스 2026-05-21 WO disclosed
US-12630530-B2 FGFR inhibitor compound and use thereof HENAN MEDINNO PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2026-05-19 US disclosed
US-20260132132-A1 3A,4,5,6-TETRAHYDRO-1 H-PYRAZOLO[3,4-C]PYRIDIN-7(7AH)-ONE DERIVATIVES AS FACTOR XIIA INHIBITORS KALVISTA PHARMACEUTICALS LTD (GB) 2026-05-14 US disclosed
EP-4355748-B1 SUBSTITUTED PYRROLO[2,3-D]PYRIMIDINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION SANOFI SA (FR) 2026-05-13 EP disclosed
WO-1999031068-A1 SUBSTITUTED ISOQUINOLINE DERIVATIVES AND THEIR USE AS ANTICONVULSANTS SMITHKLINE BEECHAM PLC (GB) 1999-06-24 WO disclosed
WO-1999005143-A1 NOVEL COMPOUNDS ASTRA PHARMACEUTICALS LTD. (GB) 1999-02-04 WO disclosed
WO-1998035978-A9 AMINOOXY-MODIFIED OLIGONUCLEOTIDES 1999-01-14 WO disclosed
WO-1998035978-A1 AMINOOXY-MODIFIED OLIGONUCLEOTIDES ISIS PHARMACEUTICALS, INC. (US) 1998-08-20 WO disclosed