SCHEMBL28290056

SCHEMBL28290056

CCc1ccccc1[Si](O[SiH3])(C(C)C)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 2/20 0.34
ADRA2B P18089 2/20 0.34
ADRA2C P18825 2/20 0.34
GABRA1 P14867 2/20 0.33
GABRB2 P47870 2/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MGLL Q99685 1/20 0.32
ELANE P08246 2/20 0.31
POLB P06746 1/20 0.31
TP53 P04637 1/20 0.31
HTR1A P08908 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28728614 0.75 TSHR (0.36)
SCHEMBL28729836 0.73 GABRA1 (0.35) GABRA1GABRB2MAPTNPSR1L3MBTL1
SCHEMBL28728848 0.73 GABRA1 (0.39) ADRA2AADRA2BADRA2CGABRA1GABRB2
SCHEMBL12441757 0.69 GABRA1 (0.42) GABRA1GABRB2MAPTNPSR1L3MBTL1
SCHEMBL1562731 0.68 GABRA1 (0.38) GABRA1GABRB2MAPTNPSR1L3MBTL1
SCHEMBL669702 0.68 GABRA1 (0.38) ADRA2AADRA2BADRA2CGABRA1GABRB2
SCHEMBL27639888 0.68 GABRA1 (0.46) GABRA1GABRB2MAPTNPSR1L3MBTL1
SCHEMBL1686677 0.67 GABRA1 (0.46) GABRA1GABRB2MAPTNPSR1L3MBTL1
SCHEMBL1686693 0.67 GABRA1 (0.46) GABRA1GABRB2MAPTNPSR1L3MBTL1
SCHEMBL10709160 0.67 GABRA1 (0.41) GABRA1GABRB2MAPTNPSR1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109641482-B Preparation of cis-1, 4-polydienes having multiple silane functional groups prepared by in situ hydrosilylation of polymer glues 株式会社普利司通 2021-11-05 CN disclosed
CN-109641482-A The preparation of the cis- -1,4- polydiene of multiple silane functionals with the Si―H addition reaction in situ preparation by polymer glue 株式会社普利司通 2019-04-16 CN disclosed