Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA3 | P07451 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 3/20 | 0.56 |
| ▸ | CA6 | P23280 | 3/20 | 0.56 |
| ▸ | CA5A | P35218 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | TYR | P14679 | 3/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.56 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21798645 | 1.00 | APP (1.00) | APPKDM4EALDH1A1MAPTCYP2C9 | |
| SCHEMBL5179114 | 0.97 | APP (0.94) | APPKDM4EALDH1A1MAPTCYP2C9 | |
| SCHEMBL11439096 | 0.97 | APP (0.94) | APPKDM4EALDH1A1MAPTCYP2C9 | |
| SCHEMBL15272541 | 0.88 | ALDH1A1 (0.83) | APPKDM4EALDH1A1MAPTCYP2C9 | |
| SCHEMBL6194091 | 0.88 | ALDH1A1 (0.83) | APPKDM4EALDH1A1MAPTCYP2C9 | |
| SCHEMBL3218153 | 0.88 | APP (0.77) | APPKDM4EALDH1A1MAPTCYP2C9 | |
| SCHEMBL303940 | 0.87 | APP (0.76) | APPKDM4EALDH1A1MAPTCYP2C9 | |
| SCHEMBL2631908 | 0.87 | APP (0.76) | APPKDM4EALDH1A1MAPTCYP2C9 | |
| SCHEMBL13359845 | 0.87 | APP (0.76) | APPKDM4EALDH1A1MAPTCYP2C9 | |
| SCHEMBL2632277 | 0.85 | APP (0.73) | APPKDM4EALDH1A1MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858072-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-12-28 | — | — | US | disclosed |
| US-20060269474-A1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060269474-A1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | APP, APBA1, PSEN1 | APP 1/4885KDM4E 4425/4885ALDH1A1 3258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.