Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28288679 | 0.81 | ATM (0.39) | FDPSATMALDH1A1MAPTTHRB | |
| SCHEMBL28288696 | 0.81 | KIF11 (0.31) | ALDH1A1THRBKMT2A | |
| SCHEMBL28355645 | 0.80 | HCAR2 (0.43) | FDPSHCAR2 | |
| SCHEMBL6347498 | 0.80 | HCAR2 (0.43) | FDPSHCAR2 | |
| SCHEMBL9543356 | 0.73 | FDPS (0.36) | FDPSALDH1A1KMT2ATSHR | |
| SCHEMBL20820038 | 0.72 | SMPD1 (0.40) | FDPSTSHR | |
| SCHEMBL28179501 | 0.72 | FDPS (0.35) | FDPSALDH1A1KMT2ATSHR | |
| SCHEMBL28001874 | 0.68 | FDPS (0.38) | FDPSALDH1A1KMT2ATSHR | |
| SCHEMBL17695127 | 0.66 | KIF11 (0.34) | ALDH1A1GABRR1TSHR | |
| SCHEMBL5029032 | 0.66 | FDPS (0.45) | FDPSALDH1A1THRBKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109694362-B | 3-arylbenzofuranone propionamide compound, composition formed by same, preparation method and application thereof | 江苏裕事达新材料科技有限责任公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-109694362-A | 3- arylben-zofuranone propanamide compounds, its composition constituted and its preparation method and application | 优缔新材料科技(苏州)有限公司 | 2019-04-30 | — | — | CN | disclosed |