Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18701663 | 0.82 | POLB (0.37) | L3MBTL1POLBTDP1PKMKDM4E | |
| SCHEMBL28291558 | 0.78 | POLB (0.51) | L3MBTL1POLBTDP1PKMKDM4E | |
| SCHEMBL3836429 | 0.77 | POLB (0.55) | L3MBTL1POLBTDP1PKMKDM4E | |
| SCHEMBL18701639 | 0.76 | TSHR (0.43) | L3MBTL1POLBTDP1PKMKDM4E | |
| SCHEMBL1371512 | 0.76 | POLB (0.53) | L3MBTL1POLBTDP1PKMKDM4E | |
| SCHEMBL18152986 | 0.76 | GPR35 (0.46) | L3MBTL1POLBTDP1PKMKDM4E | |
| Hydrochloric Acid SCHEMBL7810688 | 0.76 | POLB (0.53) | L3MBTL1POLBTDP1PKMKDM4E | |
| SCHEMBL6492073 | 0.76 | POLB (0.53) | L3MBTL1POLBTDP1PKMKDM4E | |
| SCHEMBL17479405 | 0.75 | POLB (0.37) | L3MBTL1POLBTDP1PKMKDM4E | |
| SCHEMBL3636522 | 0.74 | L3MBTL1 (0.52) | L3MBTL1POLBTDP1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563094-A | Acyclic derivatives, their preparation method and the pharmaceutical composition containing them that new (miscellaneous) aryl replaces | 法国施维雅药厂 | 2019-04-02 | — | — | CN | disclosed |