Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27474907 | 0.83 | CYP1A2 (0.45) | CYP1A2CYP3A4PTGS2PTGS1ALDH1A1 | |
| SCHEMBL5700053 | 0.75 | PTGS2 (0.59) | L3MBTL1LMNANPSR1PTGS2PTGS1 | |
| SCHEMBL9164957 | 0.75 | LMNA (0.72) | L3MBTL1LMNANPSR1CYP1A2CYP3A4 | |
| SCHEMBL28026385 | 0.73 | NPSR1 (0.49) | L3MBTL1LMNANPSR1PTGS2PTGS1 | |
| SCHEMBL19066249 | 0.73 | LMNA (0.52) | L3MBTL1LMNANPSR1POLB | |
| SCHEMBL9028766 | 0.72 | ATM (0.46) | CYP1A2CYP3A4CLK4TSHRALDH1A1 | |
| SCHEMBL14803582 | 0.71 | ATM (0.42) | LMNACYP1A2CYP3A4CLK4TSHR | |
| SCHEMBL5700446 | 0.70 | PTGS2 (0.51) | L3MBTL1LMNAPTGS2PTGS1POLB | |
| SCHEMBL8148245 | 0.70 | CYP17A1 (0.37) | L3MBTL1LMNACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL5215089 | 0.70 | MAPK9 (0.56) | CYP1A2CYP3A4CLK4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689659-A | Imidazo oxazole derivatives with antitumous effect and the pharmaceutical composition including it | 韩国科学技术研究院 | 2019-04-26 | — | — | CN | disclosed |