Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 17/20 | 0.68 |
| ▸ | IDO1 | P14902 | 15/20 | 0.62 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28288947 | 0.85 | TDO2 (0.64) | TDO2IDO1PDGFRBPDGFRA | |
| SCHEMBL348727 | 0.80 | TDO2 (0.60) | TDO2IDO1ESR1ESR2 | |
| SCHEMBL31416493 | 0.71 | TDO2 (0.56) | TDO2IDO1PDGFRBPDGFRAFYN | |
| SCHEMBL28290268 | 0.71 | TDO2 (0.65) | TDO2IDO1 | |
| SCHEMBL30081970 | 0.70 | TDO2 (0.69) | TDO2IDO1 | |
| SCHEMBL348838 | 0.68 | TDO2 (0.52) | TDO2IDO1FYN | |
| SCHEMBL1477546 | 0.67 | MAOB (0.57) | ESR1ESR2 | |
| SCHEMBL8499328 | 0.67 | SMN1; SMN2 (0.72) | TDO2IDO1PDGFRBPDGFRA | |
| SCHEMBL13730043 | 0.67 | NPC1 (0.49) | TDO2IDO1 | |
| SCHEMBL5422445 | 0.66 | NPC1 (0.45) | TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776413-A | Isoquinoline derivative with hypoglycemic activity and application | 天津科技大学 | 2019-05-21 | — | — | CN | disclosed |