Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10290412 | 0.95 | LMNA (0.54) | LMNAPOLBALDH1A1CNR2CYP1A2 | |
| SCHEMBL28662047 | 0.91 | LMNA (0.42) | LMNAPOLBALDH1A1CNR2CYP1A2 | |
| SCHEMBL19287583 | 0.82 | LMNA (0.50) | LMNAPOLBALDH1A1CNR2CYP1A2 | |
| SCHEMBL17242140 | 0.80 | ALDH1A1 (0.49) | ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL2905444 | 0.80 | ALDH1A1 (0.49) | ALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL16294838 | 0.79 | MEN1 (0.33) | LMNAPOLBALDH1A1CNR2MEN1 | |
| SCHEMBL16294690 | 0.79 | MEN1 (0.33) | LMNAPOLBALDH1A1CNR2MEN1 | |
| SCHEMBL15135511 | 0.79 | ALDH1A1 (0.60) | LMNAPOLBALDH1A1 | |
| SCHEMBL16330204 | 0.78 | LMNA (0.43) | LMNAPOLBALDH1A1CNR2CYP1A2 | |
| SCHEMBL16015420 | 0.78 | LMNA (0.58) | LMNAPOLBALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563103-A | modulators of beta-3 adrenergic receptors for the treatment or prevention of disorders related thereto | 艾尼纳制药公司 | 2019-04-02 | — | — | CN | disclosed |