Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 7/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275988 | 0.88 | TPSAB1 (0.51) | TPSAB1TPSD1TPSG1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL18167985 | 0.86 | TPSAB1 (0.50) | TPSAB1TPSD1TPSG1ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL28934495 | 0.84 | PKM (0.47) | PKMTPSAB1TPSD1TPSG1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL27952949 | 0.83 | TPSAB1 (0.42) | PKMTPSAB1TPSD1TPSG1POLB | |
| Hydrochloric Acid SCHEMBL18824267 | 0.80 | TPSAB1 (0.45) | TPSAB1TPSD1TPSG1ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL25195860 | 0.79 | PKM (0.44) | PKMTPSAB1TPSD1TPSG1HPGD | |
| Trifluoroacetic Acid SCHEMBL907665 | 0.78 | PKM (0.43) | PKMTPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL10618753 | 0.78 | TPSAB1 (0.41) | TPSAB1TPSD1TPSG1ALDH1A1CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL22123169 | 0.77 | PKM (0.43) | PKMTPSAB1TPSD1TPSG1HRH4 | |
| Trifluoroacetic Acid SCHEMBL27188793 | 0.77 | PKM (0.43) | PKMTPSAB1TPSD1TPSG1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563092-B | 2-phenylimidazo [4,5-B ] pyridin-7-amine derivatives useful as inhibitors of the activity of the mammalian tyrosine kinase ROR1 | 坎塞拉有限公司 | 2021-09-14 | — | — | CN | disclosed |
| CN-109563092-A | It can be used as the 2- phenylimidazole of the active inhibitor of mammal tyrosine kinase ROR1 simultaneously [4,5-B] pyridine -7- amine derivative | 坎塞拉有限公司 | 2019-04-02 | — | — | CN | disclosed |