Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28289076 | 0.96 | MEN1 (0.43) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL28290457 | 0.90 | MEN1 (0.41) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL28278636 | 0.85 | GNAO1 (0.46) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL27844340 | 0.84 | HRH2 (0.42) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10927121 | 0.83 | CXCR4 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2CXCR4 | |
| Tert-Butyl Formate SCHEMBL27601010 | 0.82 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL27722002 | 0.82 | TDP1 (0.39) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL27904056 | 0.82 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8321073 | 0.81 | CXCR4 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2CXCR4 | |
| SCHEMBL22266289 | 0.81 | CXCR4 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563092-A | It can be used as the 2- phenylimidazole of the active inhibitor of mammal tyrosine kinase ROR1 simultaneously [4,5-B] pyridine -7- amine derivative | 坎塞拉有限公司 | 2019-04-02 | — | — | CN | disclosed |