Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 2/20 | 0.44 |
| ▸ | ACACA | Q13085 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.41 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29662015 | 0.89 | ACACA (0.50) | PDE10AACACALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL7250047 | 0.89 | ACACA (0.50) | PDE10AACACALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL28204601 | 0.89 | ACACA (0.45) | PDE10ATOP1ACACALMNAKDM4E | |
| SCHEMBL28659827 | 0.82 | TOP1 (0.59) | TOP1LMNAKDM4ESMN1; SMN2HSP90AA1 | |
| SCHEMBL31096961 | 0.81 | TOP1 (0.58) | TOP1ACACALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL29551682 | 0.81 | TOP1 (0.58) | TOP1ACACALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL22249955 | 0.81 | TOP1 (0.58) | TOP1ACACALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL1672334 | 0.81 | PDE10A (0.57) | PDE10ALMNAKDM4ESMN1; SMN2CYP19A1 | |
| Hydrochloric Acid SCHEMBL28789582 | 0.80 | PDE10A (0.56) | PDE10ALMNAKDM4ESMN1; SMN2CYP19A1 | |
| Hydrochloric Acid SCHEMBL2953393 | 0.80 | PDE10A (0.56) | PDE10ALMNAKDM4ESMN1; SMN2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608458-B | 1, 10-phenanthroline derivative metal organic complex and preparation method thereof | 吉林大学 | 2021-03-05 | — | — | CN | disclosed |
| CN-109608458-A | 1,10- Féraud derivative metal organic coordination compound and preparation method thereof | 吉林大学 | 2019-04-12 | — | — | CN | disclosed |