SCHEMBL1672334

SCHEMBL1672334

COc1ccccc1-c1ccc2ccc3cccnc3c2n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 1/20 0.57
SMN1; SMN2 Q16637 4/20 0.50
LMNA P02545 2/20 0.50
KDM4E B2RXH2 2/20 0.50
TP53 P04637 2/20 0.50
HSP90AA1 P07900 2/20 0.50
GMNN O75496 1/20 0.50
MMP2 P08253 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
MMP9 P14780 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
NFKB1 P19838 1/20 0.50
MMP8 P22894 1/20 0.50
CCR1 P32246 1/20 0.50
THPO P40225 1/20 0.50
MTOR P42345 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28789582 0.98 PDE10A (0.56) PDE10ASMN1; SMN2LMNAKDM4ETP53
Hydrochloric Acid SCHEMBL2953393 0.98 PDE10A (0.56) PDE10ASMN1; SMN2LMNAKDM4ETP53
SCHEMBL3192555 0.90 ALDH1A1 (0.52) SMN1; SMN2LMNAKDM4EHSP90AA1MAPT
SCHEMBL2036823 0.85 MCHR1 (0.57) PDE10ASMN1; SMN2HSP90AA1MAPTALOX15
SCHEMBL18221300 0.85 PDE5A (0.49) PDE10ASMN1; SMN2LMNAKDM4ETP53
SCHEMBL8544603 0.82 PDE10A (0.57) PDE10ASMN1; SMN2LMNAKDM4ETP53
SCHEMBL12853992 0.81 LMNA (0.64) PDE10ASMN1; SMN2LMNAKDM4ETP53
SCHEMBL14900783 0.81 LMNA (0.64) PDE10ASMN1; SMN2LMNAKDM4ETP53
SCHEMBL19630330 0.81 HSP90AA1 (0.52) PDE10ASMN1; SMN2HSP90AA1MAPTALOX15
SCHEMBL28290618 0.81 PDE10A (0.45) PDE10ASMN1; SMN2LMNAKDM4EHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111217840-B Linear phenanthroline copper complex and preparation method and application thereof 浙江工业大学 2023-03-14 CN disclosed
CN-111100124-B Linear o-phenanthroline compound and preparation method and application thereof 浙江工业大学 2021-12-07 CN disclosed
CN-111217840-A Linear phenanthroline copper complex and preparation method and application thereof 浙江工业大学 2020-06-02 CN disclosed
CN-111100124-A Linear o-phenanthroline compound and preparation method and application thereof 浙江工业大学 2020-05-05 CN disclosed
CN-106986870-B Organic electric field color changing device and o-diazaphenanthrene based compound used for the same 机光科技股份有限公司 2019-07-12 CN disclosed
US-9831444-B1 Phenanthroline-based compound for organic electroluminescence device UDC IRELAND LIMITED (IE) 2017-11-28 US disclosed
US-9831444-B1 Phenanthroline-based compound for organic electroluminescence device UDC IRELAND LIMITED (IE) 2017-11-28 US disclosed
US-9831444-B1 Phenanthroline-based compound for organic electroluminescence device UDC IRELAND LIMITED (IE) 2017-11-28 US disclosed
CN-106986870-A Organic electric field color changing device and o-diazaphenanthrene based compound used for the same 机光科技股份有限公司 2017-07-28 CN disclosed
EP-2232612-B1 OLED DEVICE EMPLOYING ALKALI METAL CLUSTER COMPOUNDS GLOBAL OLED TECHNOLOGY LLC (US) 2017-02-08 EP disclosed
US-8956738-B2 Organic element for low voltage electroluminescent devices GLOBAL OLED TECHNOLOGY LLC (US) 2015-02-17 US disclosed
US-8900722-B2 OLED device employing alkali metal cluster compounds GLOBAL OLED TECHNOLOGY LLC (US) 2014-12-02 US disclosed
US-8900722-B2 OLED device employing alkali metal cluster compounds GLOBAL OLED TECHNOLOGY LLC (US) 2014-12-02 US disclosed
EP-2485892-A1 ORGANIC ELEMENT FOR LOW VOLTAGE ELECTROLUMINESCENT DEVICES Global OLED Technology LLC (US) 2012-08-15 EP disclosed
WO-2011044009-A1 ORGANIC ELEMENT FOR LOW VOLTAGE ELECTROLUMINESCENT DEVICES GLOBAL OLED TECHNOLOGY LLC (US) 2011-04-14 WO disclosed
US-20100019671-A1 ORGANIC ELEMENT FOR LOW VOLTAGE ELECTROLUMINESCENT DEVICES EASTMAN KODAK COMPANY 2010-01-28 US disclosed
US-20090142618-A1 OLED DEVICE EMPLOYING ALKALI METAL CLUSTER COMPOUNDS GLOBAL OLED TECHNOLOGY LLC 2009-06-04 US disclosed
US-20090142618-A1 OLED DEVICE EMPLOYING ALKALI METAL CLUSTER COMPOUNDS GLOBAL OLED TECHNOLOGY LLC 2009-06-04 US disclosed
WO-2009054905-A1 OLED DEVICE WITH FLUORANTHENE ELECTRON TRANSPORT MATERIALS EASTMAN KODAK COMPANY (US) 2009-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090142618-A1 OLED DEVICE EMPLOYING ALKALI METAL CLUSTER COMPOUNDS OCIAD2, OCIAD1, OSTC PDE10A 4870/4885SMN1; SMN2 4517/4885LMNA 4600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.