Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21558455 | 0.86 | KDM4E (0.54) | KDM4EGAAMAPTLMNAALDH1A1 | |
| SCHEMBL28567397 | 0.85 | ALDH1A1 (0.46) | KDM4EGAAMAPTLMNAALDH1A1 | |
| SCHEMBL9472318 | 0.82 | TSHR (0.49) | KDM4EGAAMAPTLMNAALDH1A1 | |
| SCHEMBL1125718 | 0.80 | ALDH1A1 (0.55) | KDM4EGAAMAPTLMNAALDH1A1 | |
| SCHEMBL4363481 | 0.80 | ALDH1A1 (0.67) | KDM4EGAAMAPTLMNAALDH1A1 | |
| SCHEMBL1748693 | 0.80 | LMNA (0.51) | KDM4EGAAMAPTLMNAALDH1A1 | |
| SCHEMBL5952401 | 0.79 | MAPT (0.59) | KDM4EGAAMAPTLMNAALDH1A1 | |
| SCHEMBL7242040 | 0.79 | ALDH1A1 (0.63) | KDM4EGAAMAPTLMNAALDH1A1 | |
| SCHEMBL1881661 | 0.79 | LMNA (0.50) | KDM4EGAAMAPTLMNAALDH1A1 | |
| SCHEMBL20505239 | 0.79 | LMNA (0.59) | KDM4EGAALMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109704988-A | Double hydrazone compounds and its derivative and application with aβ protein and Tau albumen with high-affinity | 北京师范大学 | 2019-05-03 | — | — | CN | disclosed |