SCHEMBL28290766

SCHEMBL28290766

[CH2]CC(C)n1cnc([N+](=O)[O-])c1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
PKM P14618 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.36
MAPK1 P28482 1/20 0.34
ATM Q13315 1/20 0.34
TAAR1 Q96RJ0 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28407960 0.81 ALDH1A1 (0.40) ALDH1A1PKML3MBTL1TAAR1HTR2A
SCHEMBL574245 0.81 ALDH1A1 (0.40) ALDH1A1PKML3MBTL1TAAR1HTR2A
SCHEMBL1799400 0.77 ALDH1A1 (0.39) ALDH1A1PKML3MBTL1TAAR1HTR2A
SCHEMBL1796846 0.77 ALDH1A1 (0.44) ALDH1A1PKML3MBTL1HTR2AHTR2C
SCHEMBL11412833 0.76 ALDH1A1 (0.41) ALDH1A1PKML3MBTL1MAPK1TAAR1
SCHEMBL27453998 0.74 HTR2A (0.35) ALDH1A1PKML3MBTL1TAAR1HTR2A
SCHEMBL27299166 0.73 L3MBTL1 (0.38) ALDH1A1PKML3MBTL1TAAR1HTR2A
SCHEMBL2999902 0.72 HTR2A (0.34) ALDH1A1PKML3MBTL1HTR2AHTR2C
SCHEMBL11416392 0.72 MAPT (0.37) ALDH1A1PKML3MBTL1HTR2AHTR2C
SCHEMBL27927715 0.72 ALDH1A1 (0.34) ALDH1A1PKML3MBTL1HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109706198-A A kind of method that online enzyme process closes nitro imidazole derivatives 浙江工业大学 2019-05-03 CN disclosed