Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290800 | 0.88 | NPY2R (0.54) | ALDH1A1SMN1; SMN2NPC1MEN1KMT2A | |
| SCHEMBL28289349 | 0.84 | KMT2A (0.49) | ALDH1A1SMN1; SMN2NPC1EPHX2KMT2A | |
| SCHEMBL16752637 | 0.84 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2NPC1EPHX2MEN1 | |
| SCHEMBL30537465 | 0.80 | CA1 (0.58) | SMN1; SMN2MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL3109620 | 0.79 | KDM4E (0.42) | ALDH1A1SMN1; SMN2NPC1EPHX2MEN1 | |
| SCHEMBL11153637 | 0.78 | NPC1 (0.56) | ALDH1A1SMN1; SMN2NPC1EPHX2MEN1 | |
| SCHEMBL720271 | 0.76 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2NPC1EPHX2MEN1 | |
| SCHEMBL16423233 | 0.76 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2NPC1EPHX2MEN1 | |
| SCHEMBL28034822 | 0.74 | CA1 (0.62) | SMN1; SMN2NPC1MEN1KMT2AL3MBTL1 | |
| SCHEMBL1765176 | 0.74 | DHODH (0.60) | ALDH1A1SMN1; SMN2NPC1EPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003104-A | Salicyclic acid derivatives, its pharmaceutically acceptable salt, its composition and its application method | 多伦多大学管理委员会 | 2019-07-12 | — | — | CN | disclosed |
| CN-105120854-B | Novel salicylic acid derivatives, pharmaceutically acceptable salts thereof, compositions thereof, and methods of use thereof | 多伦多大学管理委员会 | 2019-04-09 | — | — | CN | disclosed |