Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CASR | P41180 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290816 | 0.88 | ALDH1A1 (0.52) | SMN1; SMN2NPC1GAATSHRALDH1A1 | |
| SCHEMBL28289349 | 0.87 | KMT2A (0.49) | SMN1; SMN2RAB9ANPC1GAAMAPT | |
| SCHEMBL5114854 | 0.82 | HTR1E (0.69) | NPY2RSMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL15943121 | 0.78 | MAPT (0.49) | NPY2RSMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL11256349 | 0.77 | SMN1; SMN2 (0.59) | NPY2RSMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL30537465 | 0.76 | CA1 (0.58) | SMN1; SMN2GAAMAPTKDM4EMEN1 | |
| SCHEMBL771186 | 0.76 | MAPT (0.66) | SMN1; SMN2RAB9ANPC1MAPTTSHR | |
| SCHEMBL28290801 | 0.74 | RAB9A (0.53) | SMN1; SMN2RAB9ANPC1GAAMAPT | |
| SCHEMBL28891987 | 0.74 | TSHR (0.64) | SMN1; SMN2RAB9AGAAMAPTTSHR | |
| SCHEMBL9911362 | 0.74 | RAB9A (0.60) | SMN1; SMN2RAB9ANPC1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003104-A | Salicyclic acid derivatives, its pharmaceutically acceptable salt, its composition and its application method | 多伦多大学管理委员会 | 2019-07-12 | — | — | CN | disclosed |
| CN-105120854-B | Novel salicylic acid derivatives, pharmaceutically acceptable salts thereof, compositions thereof, and methods of use thereof | 多伦多大学管理委员会 | 2019-04-09 | — | — | CN | disclosed |