Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | PI4KA | P42356 | 5/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 5/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626823 | 0.81 | CDK1 (0.44) | CDK1ADORA1ADORA2ACCNB1CCNE1 | |
| SCHEMBL26027582 | 0.79 | CDK1 (0.43) | CDK1ADORA1ADORA2ACCNB1CCNE1 | |
| SCHEMBL4402870 | 0.79 | CDK1 (0.66) | CDK1ADORA1ADORA2ACCNB1CCNE1 | |
| SCHEMBL20049722 | 0.76 | PI4KA (0.45) | CDK1ADORA1ADORA2ACCNB1CCNE1 | |
| SCHEMBL24377187 | 0.75 | CDK1 (0.40) | CDK1ADORA1ADORA2ACCNB1CCNE1 | |
| SCHEMBL784159 | 0.75 | CDK2 (0.73) | CDK1ADORA1ADORA2ACCNB1CCNE1 | |
| SCHEMBL12379146 | 0.75 | PI4KA (0.60) | CDK1ADORA1ADORA2ACCNB1CCNE1 | |
| SCHEMBL6013684 | 0.75 | CDK1 (0.54) | CDK1ADORA1ADORA2ACCNB1CCNE1 | |
| SCHEMBL15354451 | 0.75 | CDK1 (0.73) | CDK1ADORA1ADORA2ACCNB1CCNE1 | |
| SCHEMBL24338022 | 0.75 | CDK1 (0.50) | CDK1ADORA1ADORA2ACCNB1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036107-A | TCR α homing endonuclease variants | 蓝鸟生物公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-109689865-A | BCL11A HOMING ENDONUCLEASE VARIANTS, COMPOSITIONS, AND METHODS OF USE | 蓝鸟生物公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-109475640-A | Mixed carrier for nucleic acid carried article | 库瑞瓦格股份公司 | 2019-03-15 | — | — | CN | disclosed |