Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 5/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.54 |
| ▸ | CDK2 | P24941 | 3/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | AHCY | P23526 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626823 | 0.93 | CDK1 (0.44) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL9153899 | 0.89 | CDK1 (0.44) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL27983442 | 0.89 | CDK1 (0.59) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL15789757 | 0.79 | CDK1 (0.50) | CDK1CCNB1CCNE1CDK2HSP90AA1 | |
| SCHEMBL28070623 | 0.77 | CDK1 (0.46) | CDK1CCNB1CCNE1CDK2AHCY | |
| SCHEMBL28480707 | 0.77 | CDK1 (0.47) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL4402870 | 0.77 | CDK1 (0.66) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL26027582 | 0.77 | CDK1 (0.43) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL28290896 | 0.75 | CDK1 (0.42) | CDK1CCNB1CCNE1CDK2ADORA2A | |
| SCHEMBL129642 | 0.74 | CDK1 (0.68) | CDK1CCNB1CCNE1CDK2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1625138-A2 | PROTECTED MONOMERS | Alnylam Pharmaceuticals Inc. (US) | 2006-02-15 | — | — | EP | claimed |
| WO-2004094345-A2 | PROTECTED MONOMERS | ALNYLAM PHARMACEUTICALS INC. (US) | 2004-11-04 | — | — | WO | claimed |