Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 6/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.45 |
| ▸ | CDK2 | P24941 | 3/20 | 0.45 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129642 | 0.82 | CDK1 (0.68) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL7626823 | 0.82 | CDK1 (0.44) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL26027582 | 0.81 | CDK1 (0.43) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL21703036 | 0.81 | CDK1 (0.47) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL790146 | 0.80 | CDK1 (0.46) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL129921 | 0.79 | CDK1 (1.00) | CDK1ADORA2AADORA1YTHDC1 | |
| SCHEMBL14131868 | 0.79 | CDK1 (0.64) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL129640 | 0.79 | CDK1 (0.64) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL130527 | 0.79 | CDK1 (0.64) | CDK1ADORA2AADORA1CCNB1CCNE1 | |
| SCHEMBL28290896 | 0.79 | CDK1 (0.42) | CDK1ADORA2AADORA1CCNB1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024119117-A1 | MODIFIED 5' CAP FOR MRNA AND METHODS OF USE THEREOF | PRIME MEDICINE, INC. (US) | 2024-06-06 | — | — | WO | disclosed |
| WO-2023178133-A9 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| WO-2023178133-A1 | COMPOUNDS AND METHODS FOR TREATING DISEASE | ROME THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| EP-4234565-A2 | HIGHLY ACTIVE COMPOUNDS AGAINST COVID-19 | ATEA Pharmaceuticals, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022083584-A1 | MULTIFUNCTIONAL CYCLIC DINUCLEOTIDE AND USE THEREOF | 泰励生物科技（上海）有限公司 | 2022-04-28 | — | — | WO | disclosed |
| CN-110191882-A | Novel heterocyclic compounds, preparation method and the pharmaceutical composition comprising it | 株式会社大熊制药 | 2019-08-30 | — | — | CN | disclosed |
| US-20180110783-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS SA (CH) | 2018-04-26 | — | — | US | disclosed |
| CN-107406462-A | Tricyclic DLK inhibitors and uses thereof | 豪夫迈·罗氏有限公司 | 2017-11-28 | — | — | CN | disclosed |
| CN-107337659-A | Compounds as protein kinase modulators | 理森制药股份公司 | 2017-11-10 | — | — | CN | disclosed |
| WO-2017176999-A1 | GLYCOSYLATED OLIGONUCLEOTIDES THAT MIMIC THE HIV-1 EPITOPE OF NEUTRAULIZING MONOCLONAL ANTIBODY 2G12 | BRANDEIS UNIVERSITY (US) | 2017-10-12 | — | — | WO | disclosed |
| US-20100069260-A1 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS | GUENTHER RICHARD H | 2010-03-18 | — | — | US | disclosed |
| US-20100069260-A1 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS | GUENTHER RICHARD H | 2010-03-18 | — | — | US | disclosed |
| US-7598040-B2 | Compositions and methods for the identification of inhibitors of protein synthesis | TRANA DISCOVERY, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7598040-B2 | Compositions and methods for the identification of inhibitors of protein synthesis | TRANA DISCOVERY, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| WO-2009106419-A1 | NEW MACROLIDES AND THEIR USE | BASILEA PHARMACEUTICA AG (CH) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009098320-A2 | MACROLIDES AND USES OF MACROLIDES | BASILEA PHARMACEUTICA AG (CH) | 2009-08-13 | — | — | WO | disclosed |
| US-20080199870-A1 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS | TRANA DISCOVERY, INC. | 2008-08-21 | — | — | US | disclosed |
| US-20080199870-A1 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS | TRANA DISCOVERY, INC. | 2008-08-21 | — | — | US | disclosed |
| WO-2008064304-A9 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS | TRANA DISCOVERY INC (US) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008064304-A2 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS | TRANA DISCOVERY, INC. (US) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069260-A1 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS | NSUN3, RNGTT, TARBP1 | CDK1 898/4885ADORA2A 3825/4885ADORA1 4078/4885 |
| US-20180110783-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | PRKCA, PRKCH, PRKCB | CDK1 244/4885ADORA2A 1821/4885ADORA1 3736/4885 |
| US-20080199870-A1 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS | NSUN3, RNGTT, TARBP1 | CDK1 898/4885ADORA2A 3825/4885ADORA1 4078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.