SCHEMBL28290898

SCHEMBL28290898

Cc1nc(N)c2[nH]c(S)nc2n1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 1/20 0.36
TLR7 Q9NYK1 1/20 0.32
ADORA1 P30542 3/20 0.31
ADORA3 P0DMS8 2/20 0.31
ADORA2A P29274 2/20 0.31
ADORA2B P29275 2/20 0.31
NUDT1 P36639 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20566 0.79 NUDT1 (0.47) NPY5RTLR7ADORA1ADORA3ADORA2A
SCHEMBL1766004 0.79 PDPK1 (0.44)
SCHEMBL1898084 0.72 NUDT1 (0.41) NUDT1
Hydrochloric Acid SCHEMBL7735735 0.72 ADORA1 (0.49) NPY5RTLR7ADORA1ADORA3ADORA2A
SCHEMBL3916442 0.68 ADORA1 (0.30) ADORA1ADORA3ADORA2A
SCHEMBL843169 0.68 ADORA2A (0.61) ADORA1ADORA2ANUDT1
SCHEMBL27481634 0.68 NUDT1 (0.44) ADORA1ADORA3ADORA2ANUDT1
SCHEMBL4940124 0.65 NPY5R (0.33) NPY5RTLR7ADORA1
SCHEMBL4330004 0.65 HSP90AB1 (0.33) ADORA1ADORA3ADORA2A
SCHEMBL27894362 0.64 CYP1A2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110036107-A TCR α homing endonuclease variants 蓝鸟生物公司 2019-07-19 CN disclosed
CN-109689865-A BCL11A HOMING ENDONUCLEASE VARIANTS, COMPOSITIONS, AND METHODS OF USE 蓝鸟生物公司 2019-04-26 CN disclosed
CN-109475640-A Mixed carrier for nucleic acid carried article 库瑞瓦格股份公司 2019-03-15 CN disclosed