SCHEMBL843169

SCHEMBL843169

Nc1ncnc2nc(S)[nH]c12

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.61
ADORA1 P30542 1/20 0.61
NUDT1 P36639 2/20 0.56
PI4KA P42356 8/20 0.53
PI4K2B Q8TCG2 8/20 0.53
PI4K2A Q9BTU6 8/20 0.53
PI4KB Q9UBF8 8/20 0.53
LMNA P02545 3/20 0.47
TSHR P16473 2/20 0.47
DRD3 P35462 1/20 0.47
XDH P47989 1/20 0.47
LRRK2 Q5S007 1/20 0.47
ERBB2 P04626 1/20 0.45
HSP90AA1 P07900 1/20 0.45
HSP90AB1 P08238 1/20 0.45
APEX1 P27695 1/20 0.44
ALDH1A1 P00352 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ERAP1 Q9NZ08 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8342350 0.90 ADORA2A (0.81) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL3799507 0.79 ADORA2A (0.37) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL42314 0.79 ADORA2A (0.66) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL29400753 0.79 ADORA2A (0.66) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL30109321 0.78 NUDT1 (0.68) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL1059581 0.78 NUDT1 (0.68) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL842440 0.76 ADORA2A (0.61) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL94915 0.76 ADORA2A (0.35) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL8566 0.76 ADORA2A (1.00) ADORA2AADORA1NUDT1PI4KAPI4K2B
SCHEMBL6360434 0.76 NUDT1 (0.36) ADORA2AADORA1NUDT1PI4KAPI4K2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 571 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250237947-A1 Dry Film Resist, Photosensitive Dry Film, and Copper Clad Laminate HANGZHOU FIRST ELECTRONIC MATERIAL CO., LTD (CN) 2025-07-24 US claimed
WO-2023185530-A1 DRY FILM RESIST, PHOTOSENSITIVE DRY FILM, AND COPPER CLAD LAMINATE 杭州福斯特电子材料有限公司 2023-10-05 WO claimed
WO-2023058962-A1 SURFACE ENHANCED RAMAN SCATTERING-BASED TARGET VIRUS IMMUNOASSAY 한국생명공학연구원 2023-04-13 WO claimed
CN-114660895-A Dry film resist, photosensitive dry film and copper-clad plate 杭州福斯特电子材料有限公司 2022-06-24 CN claimed
CN-109659546-B Sulfur/nitrogen/silicon co-doped graphite composite negative electrode material and preparation method thereof 成都爱敏特新能源技术有限公司 2021-11-23 CN claimed
CN-107603976-B Methods and compositions for RNA-directed target DNA modification and transcriptional regulation 埃玛纽埃尔·沙尔庞捷 2021-10-12 CN claimed
CN-109659546-A A kind of sulphur/nitrogen/silicon coblended composite cathode material of silicon/carbon/graphite and preparation method thereof 成都爱敏特新能源技术有限公司 2019-04-19 CN claimed
US-9725474-B2 Modified nucleic acid TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-08-08 US claimed
EP-2694524-B1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES US HEALTH (US) 2016-05-18 EP claimed
US-9284343-B2 2′-O-aminooxymethyl nucleoside derivatives for use in the synthesis and modification of nucleosides, nucleotides and oligonucleotides THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2016-03-15 US claimed
US-20050191665-A1 Composite organic-inorganic nanoclusters INTEL CORPORATION 2005-09-01 US claimed
WO-2005066612-A2 DETECTION OF BIOMOLECULES USING POROUS BIOSENSORS AND RAMAN SPECTROSCOPY INTEL CORPORATION (A DELAWARE CORPORATION) (US) 2005-07-21 WO claimed
US-20050147963-A1 Composite organic-inorganic nanoparticles and methods for use thereof INTEL CORPORATION (US) 2005-07-07 US claimed
US-20050142567-A1 Composite organic-inorganic nanoparticles and methods for use thereof INTEL CORPORATION (US) 2005-06-30 US claimed
US-20020094334-A1 Selective destruction of cells infected with human immunodeficiency virus BATTELLE ENERGY ALLIANCE, LLC 2002-07-18 US claimed
US-6369237-B1 ENZYME INHIBITORS OF DNA GLYCOLASE PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2002-04-09 US claimed
WO-2001060393-A1 SELECTIVE DESTRUCTION OF CELLS INFECTED WITH HUMAN IMMUNODEFICIENCY VIRUS BECHTEL BWXT IDAHO, LLC (US) 2001-08-23 WO claimed
WO-1998039334-A9 DNA GLYCOSYLASE INHIBITORS, AND USES RELATED THERETO 1999-02-18 WO claimed
WO-1998039334-A1 DNA GLYCOSYLASE INHIBITORS, AND USES RELATED THERETO PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1998-09-11 WO claimed
US-5118800-A Oligonucleotides possessing a primary amino group in the terminal nucleotide CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-06-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250237947-A1 Dry Film Resist, Photosensitive Dry Film, and Copper Clad Laminate PADI2, PADI4, PADI1 ADORA2A 2203/4885ADORA1 2394/4885NUDT1 1247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.