SCHEMBL28290926

SCHEMBL28290926

CC(F)(F)CCCc1cccc2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP2D6 P10635 2/20 0.44
SIGMAR1 Q99720 2/20 0.44
NQO2 P16083 1/20 0.44
GPR84 Q9NQS5 1/20 0.43
CYP2C9 P11712 1/20 0.43
MCL1 Q07820 1/20 0.43
BCHE P06276 1/20 0.42
MTNR1A P48039 2/20 0.42
REN P00797 1/20 0.42
AKR1B1 P15121 1/20 0.41
SLC18A2 Q05940 1/20 0.41
NR1I2 O75469 1/20 0.40
LMNA P02545 1/20 0.40
ADRA2A P08913 1/20 0.40
ACHE P22303 1/20 0.40
SLC6A2 P23975 1/20 0.40
HTR2A P28223 1/20 0.40
SLC6A4 P31645 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17288350 0.83 BCHE (0.45) CYP1A2CYP2C19CYP2D6SIGMAR1NQO2
SCHEMBL17288732 0.80 GPR84 (0.41) CYP1A2CYP2C19CYP2D6SIGMAR1NQO2
SCHEMBL9800436 0.79 CYP1A2 (0.58) CYP1A2CYP2C19CYP2D6SIGMAR1NQO2
SCHEMBL5830948 0.79 GPR84 (0.59) CYP1A2CYP2C19CYP2D6SIGMAR1NQO2
SCHEMBL17288450 0.79 GPR84 (0.40) CYP1A2CYP2C19CYP2D6SIGMAR1NQO2
SCHEMBL17288701 0.79 GPR84 (0.40) CYP1A2CYP2C19CYP2D6SIGMAR1NQO2
SCHEMBL5255388 0.78 CYP1A2 (0.48) CYP1A2CYP2C19CYP2D6NQO2CYP2C9
SCHEMBL2754934 0.78 CYP2D6 (0.50) CYP1A2CYP2C19CYP2D6SIGMAR1NQO2
SCHEMBL17288595 0.78 BCHE (0.44) CYP1A2CYP2C19CYP2D6SIGMAR1GPR84
SCHEMBL17288443 0.77 SIGMAR1 (0.44) CYP1A2CYP2C19CYP2D6SIGMAR1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106659161-B Amide compound and its harmful arthropod prevent and kill off purposes 住友化学株式会社 2019-08-02 CN disclosed
CN-106572659-B Harmful arthropod agent for preventing and eliminating containing amide compound 住友化学株式会社 2019-05-10 CN disclosed