Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | VDR | P11473 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2531424 | 0.96 | VDR (0.51) | PKMALDH1A1POLBHTTVDR | |
| SCHEMBL631561 | 0.95 | KMT2A (0.50) | PKMALDH1A1POLBHTTVDR | |
| Water SCHEMBL16927693 | 0.93 | KMT2A (0.49) | PKMALDH1A1POLBHTTVDR | |
| SCHEMBL5185491 | 0.92 | VDR (0.54) | PKMALDH1A1POLBHTTVDR | |
| SCHEMBL8217662 | 0.86 | CYP2D6 (0.52) | PKMALDH1A1POLBHTTVDR | |
| SCHEMBL5875363 | 0.84 | VDR (0.47) | PKMALDH1A1POLBHTTVDR | |
| SCHEMBL3739465 | 0.84 | VDR (0.51) | PKMALDH1A1POLBHTTVDR | |
| SCHEMBL890525 | 0.84 | USP2 (0.48) | PKMALDH1A1POLBHTTVDR | |
| SCHEMBL15006565 | 0.83 | VDR (0.46) | PKMALDH1A1POLBHTTVDR | |
| SCHEMBL40765 | 0.83 | VDR (0.46) | PKMALDH1A1POLBHTTVDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4366829-A1 | PHENYL ACETAMIDE BASED IL-17A MODULATORS AND USES THEREOF | Dice Alpha, Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023283453-A1 | PHENYL ACETAMIDE BASED IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| CN-109715613-A | Heterocyclic compound | 武田药品工业株式会社 | 2019-05-03 | — | — | CN | disclosed |