Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.32 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31112249 | 1.00 | ERN1 (0.44) | ERN1ALBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28991521 | 0.82 | ERN1 (0.40) | ERN1ALBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL2192714 | 0.81 | SLC6A2 (0.43) | ERN1HPGDKMT2ACES2CES1 | |
| SCHEMBL30673991 | 0.81 | SLC6A2 (0.43) | ERN1HPGDKMT2ACES2CES1 | |
| SCHEMBL678440 | 0.80 | PARP10 (0.39) | KDM4EALDH1A1CYP3A4HPGDMEN1 | |
| SCHEMBL8594043 | 0.80 | LMNA (0.54) | ERN1KDM4EALDH1A1HSD17B10LMNA | |
| SCHEMBL29364630 | 0.80 | PARP10 (0.39) | KDM4EALDH1A1CYP3A4HPGDMEN1 | |
| SCHEMBL29113033 | 0.80 | ERN1 (0.41) | ERN1ALBKDM4EALDH1A1HSD17B10 | |
| SCHEMBL25344610 | 0.80 | ALB (0.38) | ERN1ALBKDM4EHSD17B10MEN1 | |
| Ammonia Solution, Strong SCHEMBL28185694 | 0.79 | SLC6A2 (0.42) | ERN1KMT2ACES2CES1RHEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867726-B | Small molecule inhibitors of KRAS G12C mutants | 默沙东有限责任公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-114867726-A | Small molecule inhibitors of KRAS G12C mutant | 默沙东公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-109715612-A | SOMATOSTATIN MODULATORS AND USES THEREOF | 克林提克斯医药股份有限公司 | 2019-05-03 | — | — | CN | disclosed |