SCHEMBL678440

SCHEMBL678440

OB(O)Oc1ccccc1F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.39
CXCL8 P10145 1/20 0.39
ACHE P22303 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
RHEB Q15382 1/20 0.38
ALDH1A1 P00352 3/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
GAA P10253 1/20 0.37
ENPP2 Q13822 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
ORAI1 Q96D31 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364630 1.00 PARP10 (0.39) PARP10CXCL8ACHEL3MBTL1TDP1
SCHEMBL21143589 0.98 CXCL8 (0.42) PARP10CXCL8ACHEL3MBTL1TDP1
Pentane SCHEMBL6139807 0.87 L3MBTL1 (0.46) L3MBTL1TDP1KDM4ECYP1A2CYP2C9
Tromethamine SCHEMBL23467073 0.84 PARP10 (0.37) PARP10CXCL8L3MBTL1TDP1ALDH1A1
SCHEMBL31338564 0.83 ERN1 (0.36) PARP10ACHEL3MBTL1TDP1ALDH1A1
SCHEMBL2192714 0.82 SLC6A2 (0.43) ACHERHEBKMT2AHTR1ASLC6A2
SCHEMBL30673991 0.82 SLC6A2 (0.43) ACHERHEBKMT2AHTR1ASLC6A2
SCHEMBL6678412 0.82 ENPP2 (0.44) TDP1ALDH1A1GAAENPP2MEN1
SCHEMBL29706601 0.82 ENPP2 (0.44) TDP1ALDH1A1GAAENPP2MEN1
SCHEMBL31112249 0.80 ERN1 (0.44) L3MBTL1TDP1RHEBALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120157794-A Cycloolefin copolymer and preparation method thereof 万华化学集团股份有限公司 2025-06-17 CN claimed
CN-120059436-A High-transparency scratch-resistant polycarbonate material 厦门天宇新材料科技有限公司 2025-05-30 CN claimed
CN-120033221-A Silicon-based composite material, preparation method thereof and secondary battery 兰溪致德新能源材料有限公司 2025-05-23 CN claimed
CN-119708316-A Ethylene/alpha-olefin gradient copolymer and preparation method thereof 中国科学院长春应用化学研究所 2025-03-28 CN claimed
CN-119368155-A Fluorescent boron quantum dot photocatalyst and preparation method and application thereof 南京工业大学 2025-01-28 CN claimed
CN-119137161-A Palladium catalyst for vinyl addition polymer formation with improved film forming properties 普罗米鲁斯有限责任公司 2024-12-13 CN claimed
CN-118994450-A Process for preparing ultra-high molecular weight narrow distribution poly alpha-olefin 陕西煤业化工技术研究院有限责任公司 2024-11-22 CN claimed
CN-118894891-A Thioether-functionalized rare earth complex with limited geometric configuration, preparation method thereof, multipolymer and preparation method thereof 中国科学院长春应用化学研究所 2024-11-05 CN claimed
CN-118772131-A Biaryl compound and preparation method and application thereof 河南大学 2024-10-15 CN claimed
CN-116096760-B Hindered amine stabilized UV-active organopalladium catalyzed polycycloolefin compositions as optical materials 住友电木株式会社 2024-08-02 CN claimed
EP-1913005-B1 FLUOROPHENYLBORATES AND THEIR USE AS ACTIVATORS IN CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2013-07-31 EP claimed
EP-1506176-B1 AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM PFIZER ITALIA SRL (IT) 2013-04-24 EP claimed
CN-101263148-B Fluorophenylborates and their use as activators in catalyst systems for olefin polymerization EXXON MOBIL CHEM PATENTS INC 2012-06-06 CN claimed
CN-101052660-B Polymerization catalyst for conjugated diene polymer, process for producing conjugated diene polymer using the same, rubber composition for tire, and rubber composition for golf ball UBE INDUSTRIES 2010-07-14 CN claimed
CN-101263148-A Fluorophenylborates and their use as activators in catalyst systems for olefin polymerization EXXONMOBIL CHEM PATENTS INC (US) 2008-09-10 CN claimed
EP-1913005-A1 FLUOROPHENYLBORATES AND THEIR USE AS ACTIVATORS IN CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2008-04-23 EP claimed
US-7297653-B2 Fluorophenylborates and their use as activators in catalyst systems for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-20 US claimed
WO-2007018743-A1 FLUOROPHENYLBORATES AND THEIR USE AS ACTIVATORS IN CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2007-02-15 WO claimed
US-20070021575-A1 Fluorophenylborates and their use as activators in catalyst systems for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2007-01-25 US claimed
CN-1208360-C In-mold addition polymerization of norbornene-type monomers using group 10 metal complexes SUMITOMO BAKELITE CO (JP) 2005-06-29 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070021575-A1 Fluorophenylborates and their use as activators in catalyst systems for olefin polymerization ARF4, ARF1, ARFIP2 PARP10 707/4885CXCL8 4250/4885ACHE 3582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.