Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA3 | P07451 | 3/20 | 0.34 |
| ▸ | CA4 | P22748 | 3/20 | 0.34 |
| ▸ | CA6 | P23280 | 3/20 | 0.34 |
| ▸ | CA5A | P35218 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20392012 | 0.85 | — | — | |
| SCHEMBL28502362 | 0.72 | LMNA (0.44) | LMNACYP2A6CES2CES1ALDH1A1 | |
| SCHEMBL28515691 | 0.70 | LMNA (0.42) | LMNACYP2A6CES2CES1ALDH1A1 | |
| SCHEMBL24691640 | 0.67 | CES2 (0.38) | CES2CES1MEN1KMT2A | |
| 1,4-Dichlorobenzene SCHEMBL11243685 | 0.67 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL5191 | 0.67 | — | — | |
| SCHEMBL21916009 | 0.65 | CES2 (0.52) | LMNACES2CES1ALDH1A1MAPK1 | |
| 1,4-Dichlorobenzene SCHEMBL29137104 | 0.64 | LMNA (0.73) | LMNACYP2A6CES2CES1ALDH1A1 | |
| 1,4-Dichlorobenzene SCHEMBL11216474 | 0.64 | LMNA (0.73) | LMNACYP2A6CES2CES1ALDH1A1 | |
| 1,4-Dichlorobenzene SCHEMBL10603593 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651202-A | Utilize the method for dimethyl sulfoxide ylide, amine and carbon dioxide synthesis of carbamates | 华南理工大学 | 2019-04-19 | — | — | CN | disclosed |