Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6559126 | 0.86 | ESR1 (0.42) | CA1CA2PARP10KMT2AALDH1A1 | |
| SCHEMBL12229234 | 0.86 | LMNA (0.50) | CA1CA2KMT2AALDH1A1MEN1 | |
| SCHEMBL16351385 | 0.84 | ATM (0.49) | KMT2APKMALDH1A1MEN1KIF11 | |
| SCHEMBL16351387 | 0.84 | ATM (0.49) | KMT2APKMALDH1A1MEN1KIF11 | |
| SCHEMBL28292610 | 0.83 | PRSS1 (0.42) | KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8681156 | 0.82 | ATM (0.47) | KMT2APKMALDH1A1MEN1FAAH | |
| SCHEMBL28888054 | 0.81 | ALDH1A1 (0.50) | KMT2AALDH1A1LDHASLC6A4 | |
| SCHEMBL29237379 | 0.80 | PDE4B (0.46) | KMT2AALDH1A1LDHAMEN1KIF11 | |
| SCHEMBL29237375 | 0.80 | KMT2A (0.50) | CA1CA2PARP1PARP10PARP2 | |
| SCHEMBL8672997 | 0.80 | STS (0.59) | CA1CA2KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574906-A | A kind of preparation method of 3,3 '-two Indoleacetic esters | 兰州大学 | 2019-04-05 | — | — | CN | disclosed |