Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22120759 | 0.81 | CYP1A2 (0.49) | MAPTCYP1A2CYP2D6KMT2ALRRK2 | |
| SCHEMBL22122530 | 0.80 | KIF18A (0.42) | MAPTCYP1A2CYP2D6KMT2AAKT1 | |
| SCHEMBL22122528 | 0.80 | KIF18A (0.42) | MAPTCYP1A2CYP2D6KMT2AAKT1 | |
| SCHEMBL29434159 | 0.78 | MAPT (0.65) | MAPTCYP1A2CYP2D6KMT2ARAF1 | |
| SCHEMBL971891 | 0.78 | MAPT (0.65) | MAPTCYP1A2CYP2D6KMT2ARAF1 | |
| SCHEMBL29434160 | 0.78 | MAPT (0.65) | MAPTCYP1A2CYP2D6KMT2ARAF1 | |
| SCHEMBL15205935 | 0.78 | CNR2 (0.54) | — | |
| SCHEMBL1309176 | 0.77 | MAPT (0.63) | MAPTCYP1A2CYP2D6KMT2ARAF1 | |
| SCHEMBL15535335 | 0.76 | KMT2A (0.37) | MAPTCYP1A2CYP2D6KMT2AMAPK1 | |
| SCHEMBL13173926 | 0.76 | CYP1A2 (0.61) | MAPTCYP1A2CYP2D6KMT2ARAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563043-A | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | disclosed |