Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291584 | 0.82 | PKM (0.53) | MAPTTSHRKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL2027674 | 0.80 | MAPT (0.47) | MAPTTSHRKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL7670938 | 0.78 | TSHR (0.45) | MAPTTSHRKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL11888070 | 0.77 | MAPT (0.44) | MAPTTSHRKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL6593225 | 0.77 | MAPT (0.44) | MAPTTSHRKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL166726 | 0.77 | MAPT (0.54) | MAPTTSHRKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL12272176 | 0.77 | HSD17B10 (0.44) | MAPTTSHRKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL8928555 | 0.77 | MAPT (0.46) | MAPTTSHRKMT2AHSD17B10ALDH1A1 | |
| SCHEMBL9965178 | 0.77 | RAF1 (0.51) | MAPTPKMRAF1 | |
| SCHEMBL12531858 | 0.77 | MAPT (0.40) | MAPTTSHRKMT2AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563094-A | Acyclic derivatives, their preparation method and the pharmaceutical composition containing them that new (miscellaneous) aryl replaces | 法国施维雅药厂 | 2019-04-02 | — | — | CN | disclosed |