Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.39 |
| ▸ | DAO | P14920 | 5/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 2/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28291594 | 0.82 | MAPT (0.44) | PKMNPSR1RXFP1ALDH1A1LMNA | |
| SCHEMBL5104631 | 0.77 | PKM (0.52) | PKMNPSR1RXFP1ALDH1A1LMNA | |
| SCHEMBL4547877 | 0.76 | ALDH1A1 (0.55) | PKMNPSR1RXFP1ALDH1A1LMNA | |
| SCHEMBL9836065 | 0.74 | PKM (0.48) | PKMNPSR1RXFP1ALDH1A1LMNA | |
| SCHEMBL3780362 | 0.74 | GPR35 (0.48) | PKMNPSR1RXFP1ALDH1A1LMNA | |
| SCHEMBL6592873 | 0.74 | RXFP1 (0.48) | PKMNPSR1RXFP1ALDH1A1LMNA | |
| SCHEMBL12104573 | 0.74 | PKM (0.48) | PKMNPSR1RXFP1ALDH1A1LMNA | |
| SCHEMBL12104561 | 0.74 | PKM (0.49) | PKMNPSR1RXFP1ALDH1A1LMNA | |
| SCHEMBL9965184 | 0.74 | NPSR1 (0.44) | PKMNPSR1RXFP1KMT2A | |
| SCHEMBL21939099 | 0.72 | PKM (0.47) | PKMNPSR1RXFP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563094-A | Acyclic derivatives, their preparation method and the pharmaceutical composition containing them that new (miscellaneous) aryl replaces | 法国施维雅药厂 | 2019-04-02 | — | — | CN | disclosed |