Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28223666 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1PKMLMNA | |
| SCHEMBL16622399 | 0.68 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1PKMLMNA | |
| SCHEMBL19199312 | 0.64 | LMNA (0.43) | ALDH1A1KMT2AMEN1PKMLMNA | |
| SCHEMBL27945700 | 0.63 | KMT2A (0.44) | ALDH1A1KMT2AMEN1PKMLMNA | |
| SCHEMBL2385283 | 0.62 | CYP1A2 (0.62) | ALDH1A1KMT2APKMLMNACYP1A2 | |
| SCHEMBL28881213 | 0.62 | KMT2A (0.43) | ALDH1A1KMT2AMEN1PKMLMNA | |
| SCHEMBL248189 | 0.61 | — | — | |
| SCHEMBL30047247 | 0.61 | — | — | |
| SCHEMBL14480111 | 0.61 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1PKMLMNA | |
| SCHEMBL4760461 | 0.61 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105324117-B | Polysubstituted aromatic compounds as serine protease inhibitors | 维颂公司 | 2019-04-09 | — | — | CN | claimed |