SCHEMBL28291654

SCHEMBL28291654

SCC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.46
KCNN4 O15554 3/20 0.41
TSHR P16473 2/20 0.41
IDO1 P14902 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP11B1 P15538 2/20 0.39
CYP11B2 P19099 2/20 0.39
TAAR1 Q96RJ0 1/20 0.39
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6555564 0.78 KIF11 (0.54) KIF11KCNN4TSHRIDO1ALDH1A1
SCHEMBL14601175 0.78 KCNN4 (0.50) KIF11KCNN4TSHRIDO1ALDH1A1
SCHEMBL28873040 0.75 KIF11 (0.50) KIF11KCNN4TSHRALDH1A1CYP11B1
SCHEMBL1149158 0.75 KIF11 (0.64) KIF11KCNN4TSHRALDH1A1CYP11B1
SCHEMBL6831120 0.74 KCNN4 (0.39) KIF11KCNN4TSHRIDO1ALDH1A1
SCHEMBL9220501 0.74 CYP2C19 (0.37) KCNN4TSHRIDO1ALDH1A1TAAR1
SCHEMBL9106222 0.74 KIF11 (0.61) KIF11CYP11B1CYP11B2CYP2C9CYP2C19
SCHEMBL10415351 0.72 TSHR (0.50) KIF11KCNN4TSHRIDO1ALDH1A1
SCHEMBL14127528 0.72 TSHR (0.50) KIF11KCNN4TSHRIDO1ALDH1A1
SCHEMBL8730213 0.72 TAAR1 (0.58) KCNN4IDO1ALDH1A1TAAR1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110128666-B Functionalized polyethyleneimine coated nano-gold particle composite material and preparation method thereof 南京工业大学 2021-09-28 CN claimed
CN-110128666-B Functionalized polyethyleneimine coated nano-gold particle composite material and preparation method thereof 南京工业大学 2021-09-28 CN disclosed
CN-109690363-B Hard coat laminate, molded body, and method for producing same 株式会社大赛璐 2021-07-27 CN disclosed
CN-109694340-A Surface ligand, quantum dot and preparation method thereof TCL集团股份有限公司 2019-04-30 CN disclosed