Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 13/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9106222 | 0.85 | KIF11 (0.61) | KIF11SMN1; SMN2CYP11B1CYP11B2KCNH2 | |
| SCHEMBL1149158 | 0.83 | KIF11 (0.64) | KIF11SMN1; SMN2CYP11B1CYP11B2KCNH2 | |
| SCHEMBL6404738 | 0.81 | KIF11 (0.57) | KIF11KCNH2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14127464 | 0.79 | KIF11 (0.38) | KIF11SMN1; SMN2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL19730613 | 0.79 | KIF11 (0.38) | KIF11SMN1; SMN2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28291654 | 0.78 | KIF11 (0.46) | KIF11CYP11B1CYP11B2CYP2C9CYP2C19 | |
| SCHEMBL27656873 | 0.76 | KIF11 (0.62) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| SCHEMBL14127642 | 0.75 | TSHR (0.46) | KIF11SMN1; SMN2KCNH2CYP2D6CYP2C9 | |
| SCHEMBL6035962 | 0.75 | KIF11 (0.50) | KIF11SMN1; SMN2CYP11B1CYP11B2KCNH2 | |
| SCHEMBL19126253 | 0.75 | TAAR1 (0.54) | SMN1; SMN2CYP3A4CYP2D6CYP2C19KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487762-A1 | RADIOFLUORINATION METHODS | Amersham plc (GB) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080544-A1 | RADIOFLUORINATION METHODS | AMERSHAM PLC (GB) | 2003-10-02 | — | — | WO | disclosed |