Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20416589 | 0.86 | MEN1 (0.42) | KMT2AMEN1OPRM1OPRD1P2RX7 | |
| SCHEMBL20442158 | 0.82 | MEN1 (0.39) | KMT2AMEN1OPRM1OPRD1P2RX7 | |
| SCHEMBL28291731 | 0.77 | SMN1; SMN2 (0.46) | RAB9ASMN1; SMN2NPC1MAPTTSHR | |
| SCHEMBL20910181 | 0.74 | MEN1 (0.48) | KMT2AMEN1OPRM1OPRD1P2RX7 | |
| SCHEMBL28291724 | 0.72 | HSD11B1 (0.44) | KMT2AMEN1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL28293343 | 0.72 | SMN1; SMN2 (0.39) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL16132534 | 0.70 | CCR1 (0.46) | KMT2AMEN1P2RX7RAB9ASMN1; SMN2 | |
| SCHEMBL129020 | 0.70 | CCR1 (0.46) | KMT2AMEN1P2RX7RAB9ASMN1; SMN2 | |
| SCHEMBL10381880 | 0.69 | MEN1 (0.52) | KMT2AMEN1OPRM1OPRD1P2RX7 | |
| SCHEMBL3825414 | 0.69 | NOS3 (0.36) | KMT2AMEN1P2RX7RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608390-B | Synthesis method of chiral quaternary carbon pyridine beta-hydroxy ester compound | 温州大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-109608390-A | A kind of synthetic method of chirality quaternary carbon pyridines β hydroxyl esters compound | 温州大学 | 2019-04-12 | — | — | CN | disclosed |