Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704638 | 0.82 | KCNA3 (0.42) | KCNA3HTR1BDRD2DRD4DRD3 | |
| SCHEMBL920685 | 0.82 | KDM4E (0.37) | KCNA3TAAR1ALDH1A1RECQLTHRB | |
| SCHEMBL919834 | 0.79 | LTA4H (0.36) | KCNA3HTR1BDRD2DRD3HTR1D | |
| SCHEMBL919446 | 0.79 | KCNA3 (0.31) | KCNA3HTR1BHTR1D | |
| SCHEMBL919832 | 0.79 | LTA4H (0.36) | KCNA3HTR1BDRD2DRD3HTR1D | |
| SCHEMBL919448 | 0.79 | KCNA3 (0.31) | KCNA3HTR1BHTR1D | |
| SCHEMBL921745 | 0.78 | CDK1 (0.33) | KCNA3 | |
| SCHEMBL921743 | 0.78 | CDK1 (0.33) | KCNA3 | |
| SCHEMBL920804 | 0.77 | ALDH1A1 (0.45) | KCNA3HTR1BDRD2DRD4DRD3 | |
| SCHEMBL10744938 | 0.77 | ALDH1A1 (0.33) | KCNA3HTR1BDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563103-A | modulators of beta-3 adrenergic receptors for the treatment or prevention of disorders related thereto | 艾尼纳制药公司 | 2019-04-02 | — | — | CN | disclosed |