SCHEMBL282919

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10127066	0.92	ALPL (0.44)	ALKGFERRXFP1ROCK1SYK
	SCHEMBL16305333	0.90	TNNI3K (0.49)	TNNI3KBRAF
	SCHEMBL10127083	0.90	TNNI3K (0.43)	EML4ALKGFERRXFP1PDE4B
	SCHEMBL10127085	0.89	GFER (0.41)	EML4ALKGFERRXFP1PDE4B
	SCHEMBL10156583	0.89	TNNI3K (0.44)	GFERRXFP1MEN1KMT2ACCNB2
	SCHEMBL10127137	0.89	GFER (0.43)	EML4ALKGFERRXFP1PDE4B
	SCHEMBL13071118	0.88	RXFP1 (0.41)	EML4ALKGFERRXFP1PDE4B
	SCHEMBL10127028	0.87	SYK (0.41)	PDE4BSYKJAK3JAK1XDH
	SCHEMBL10127056	0.85	GFER (0.47)	ALKGFERRXFP1ROCK1SYK
	SCHEMBL10127047	0.83	GFER (0.45)	GFERRXFP1XDHMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.