Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinimide SCHEMBL3644689 | 0.88 | CRBN (0.55) | CRBNLMNAITGB3ITGB1ITGAV | |
| Acrylic Acid SCHEMBL27596888 | 0.88 | GSK3A (0.55) | GSK3AGSK3BCCR6LMNAITGB3 | |
| Acrylic Acid SCHEMBL380952 | 0.88 | GSK3A (0.55) | GSK3AGSK3BCCR6LMNAITGB3 | |
| Acrylic Acid SCHEMBL9443355 | 0.88 | GSK3A (0.55) | GSK3AGSK3BCCR6LMNAITGB3 | |
| Succinimide SCHEMBL1998492 | 0.81 | CRBN (0.65) | CRBNGSK3AGSK3BCCR6DDB1 | |
| Acrylic Acid SCHEMBL4572761 | 0.79 | CRBN (0.59) | CRBNLMNAITGB3ITGB1ITGAV | |
| Succinimide SCHEMBL6231913 | 0.79 | CRBN (0.61) | CRBNGSK3AGSK3BCCR6DDB1 | |
| Succinimide SCHEMBL28037713 | 0.74 | CRBN (0.55) | CRBNLMNAITGB3ITGB1ITGAV | |
| SCHEMBL28290551 | 0.73 | GSK3A (0.52) | GSK3AGSK3BCCR6 | |
| Succinimide SCHEMBL27701406 | 0.73 | CRBN (0.52) | CRBNITGB3ITGB1ITGAVITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608379-A | A kind of-two polyethylene glycol of protein cross agent maleimide-acrylic acid succinimide ester preparation method | 苏州昊帆生物股份有限公司 | 2019-04-12 | — | — | CN | disclosed |