SCHEMBL28292301

SCHEMBL28292301

C=C(C)C(=O)OP(=O)(OCCO)OCCCC

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.48
TSHR P16473 4/20 0.44
LPAR3 Q9UBY5 3/20 0.36
LPAR1 Q92633 2/20 0.36
LPAR2 Q9HBW0 2/20 0.36
ALDH1A1 P00352 1/20 0.35
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4965117 0.94 CYP3A4 (0.55) CYP3A4TSHRLPAR3LPAR1LPAR2
SCHEMBL28200633 0.87 THRB (0.40) CYP3A4TSHRALDH1A1THRB
SCHEMBL29259528 0.87 TSHR (0.59) CYP3A4TSHRLPAR3LPAR1LPAR2
SCHEMBL28193503 0.87 ALDH1A1 (0.37) CYP3A4TSHRALDH1A1THRB
SCHEMBL491086 0.83 TSHR (0.43) CYP3A4TSHRLPAR3LPAR1LPAR2
SCHEMBL27730736 0.82 TSHR (0.33) TSHR
SCHEMBL25398870 0.80 SMN1; SMN2 (0.39) TSHRTHRB
SCHEMBL19833987 0.80 TSHR (0.35) TSHRTHRB
SCHEMBL28068530 0.79 BTN3A1 (0.40) TSHRALDH1A1THRB
SCHEMBL9187927 0.79 CYP3A4 (0.77) CYP3A4TSHRLPAR3LPAR1LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109650762-A A kind of phosphate type polycarboxylate water-reducer and preparation method 科之杰新材料集团有限公司 2019-04-19 CN disclosed