SCHEMBL28292343

SCHEMBL28292343

[CH2]c1occ2cc(C#N)ccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.46
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
IMPDH2 P12268 1/20 0.38
IMPDH1 P20839 1/20 0.38
SLC6A4 P31645 6/20 0.37
SLC6A2 P23975 2/20 0.37
SLC6A3 Q01959 2/20 0.37
CYP19A1 P11511 1/20 0.33
NCEH1 Q6PIU2 2/20 0.32
CYP17A1 P05093 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2093471 0.74 CYP2A6 (0.42) CYP2A6CA1CA2IMPDH2IMPDH1
SCHEMBL28741075 0.74 CA1 (0.44) CYP2A6CA1CA2IMPDH2IMPDH1
SCHEMBL8712457 0.73 CYP2A6 (0.41) CYP2A6CA1CA2IMPDH2IMPDH1
SCHEMBL8713430 0.71 CA1 (0.41) CYP2A6CA1CA2IMPDH2IMPDH1
SCHEMBL8895917 0.71 CYP2A6 (0.40) CYP2A6CA1CA2IMPDH2IMPDH1
SCHEMBL28149963 0.71 CYP1A2 (0.42) CYP2A6KDM4EALDH1A1GAA
SCHEMBL27334497 0.71 CYP2A6 (0.37) CYP2A6KDM4EALDH1A1NOS1
SCHEMBL28149904 0.71 CYP1A2 (0.37) CYP2A6
SCHEMBL13037656 0.71 CA2 (0.55) CYP2A6CA1CA2IMPDH2IMPDH1
SCHEMBL9674165 0.70 CYP2A6 (0.39) CYP2A6CA1CA2IMPDH2IMPDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106572659-B Harmful arthropod agent for preventing and eliminating containing amide compound 住友化学株式会社 2019-05-10 CN disclosed