SCHEMBL8895917

SCHEMBL8895917

CC(N)c1occ2cc(C#N)ccc12

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.40
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
SLC6A4 P31645 4/20 0.34
IMPDH2 P12268 1/20 0.33
IMPDH1 P20839 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A3 Q01959 1/20 0.33
TRPV1 Q8NER1 1/20 0.32
TLR7 Q9NYK1 2/20 0.32
NCEH1 Q6PIU2 2/20 0.32
IDO1 P14902 1/20 0.30
SCN10A Q9Y5Y9 1/20 0.30
DPP4 P27487 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7618939 0.76 LMNA (0.42) CYP2A6SLC6A4SLC6A2SLC6A3
SCHEMBL28292343 0.71 CYP2A6 (0.46) CYP2A6CA1CA2SLC6A4IMPDH2
SCHEMBL2096626 0.71 CYP2A6 (0.39) CYP2A6CA1CA2SLC6A4IMPDH2
SCHEMBL3983731 0.71 SLC6A2 (0.37) CYP2A6SLC6A4SLC6A2SLC6A3
SCHEMBL28741075 0.68 CA1 (0.44) CYP2A6CA1CA2SLC6A4IMPDH2
SCHEMBL8895911 0.68 CYP2A6 (0.46) CYP2A6CA1CA2IMPDH2IMPDH1
SCHEMBL2093471 0.68 CYP2A6 (0.42) CYP2A6CA1CA2SLC6A4IMPDH2
SCHEMBL20559738 0.68 CYP2A6 (0.46) CYP2A6CA1CA2IMPDH2IMPDH1
SCHEMBL9674165 0.68 CYP2A6 (0.39) CYP2A6CA1CA2SLC6A4IMPDH2
SCHEMBL8712457 0.67 CYP2A6 (0.41) CYP2A6CA1CA2IMPDH2IMPDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587110-B1 Condensed heterocyclic derivatives and agricultural or horticultural fungicides containing the same KUMIAI CHEMICAL INDUSTRY CO (JP) 1997-12-17 EP disclosed
EP-0587110-A2 Condensed heterocyclic derivatives and agricultural or horticultural fungicides containing the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1994-03-16 EP disclosed